Protein Alignment Nepl16 and nep-11

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 838
• Identity: 168/838 - (20%)
• Similarity: 301/838 - (35%)
• Gaps: 236/838 - (28%)

  Fly    95 WLRTSAAVHKMAITSATLLVTTLLVASPILFLIST---------------------APSPLPRDC 138
            |.::...:.|:.:  ..||:..||.|..:..:|:|                     .|:..|...
 Worm    65 WWKSRTTMEKLLL--PVLLLFCLLTAVLLAVIINTDKRIEAMKTDHATQTEHAGFGDPTENPTKT 127

  Fly   139 YMDGDRCSPAV-----SAPPE-------------CSDPICEAVASSIQARLNWNKDPCTEFKKFS 185
            ..| .|..|.|     |..||             ||.|.|...|:.....:|.:.|||.:|.:|:
 Worm   128 AED-PRVPPIVPEAPTSPEPEVTTSTEKPKEPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFA 191

  Fly   186 C--WRNTPNKNITNLIEMGN---SQKSVDSQMLYLFQNKIM--NGSFGILHNLFESCLQQTTNST 243
            |  | |..:....::...|.   :::.|..|:..|.:.:::  :.|..:....:.||:.:|....
 Worm   192 CGQW-NDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQEVVTESESINMARATYRSCMNKTQLDE 255

  Fly   244 VMHRIFDSLGGYLPVGSVGPSSIAPLIAKIYDLGPSPLVD------------------------- 283
            :|                    ..||...:.:||..||:.
 Worm   256 LM--------------------TGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRRDYGVDV 300

  Fly   284 -----LYHDLSYGRRPHILL----IISGPSTSSTILERKIRWMSPKAPPSRIRQGVPKLLADLIE 339
                 :|.|.....|..:.:    :..|..|....|...:......|....:||     :|.|::
 Worm   301 FFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQ-----IAHLLK 360

  Fly   340 NFLPYFVSYAQRVSEKDTIFEFIKDLNKLQV-EHSRRGFWDSTVLYNVSSLQDLY---PVLNWT- 399
            .......|.::..::.:.|.:|..:|.|:.| |..||   ::|.|||...:||||   |.::|.
 Worm   361 TDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERR---NNTRLYNKRQIQDLYNLLPQVDWVP 422

  Fly   400 ---LLIPQNWS------GPIVVRNSDYLKALEY--------FLTKYPT-RVAHNSLLLLSA---- 442
               .:.|.:.:      ..|::...:||:.:..        .||.|.. ||..:::..|..
 Worm   423 FFQSIAPSDLTHLFHNETEIIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFED 487

  Fly   443 -----LQILPRDYPSP---EVCTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSLKAHL 499
                 |:::.....||   :.|.:.....||..:.::|:..|..|..|....|..:..::..|.|
 Worm   488 IKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADL 552

  Fly   500 KRA-----PSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQP----LNIT-----------SE 544
            .|.     ...|..|:.|.::: |.:   .|:.:.|:.|..|..    |:|:           |.
 Worm   553 VRQNDWMDEETKAVAIEKANSM-INN---IGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSV 613

  Fly   545 CW-----FQNILEIYKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFN 604
            .|     ||.:.:.:.|::.   |||           |.|...||....::|..|..::..|:|:
 Worm   614 VWMQSREFQKLTKPFDKHEF---DIS-----------PAVVNAFYSPEKNAITFPAGILQPPFFS 664

  Fly   605 AVLPPYLHYASVGVSIAKEIL---------------------RSITKSFDEKAMRCVPHSVNIFS 648
            ...|..::|.::|..|..||.                     .|...|||.: .||:   |..:.
 Worm   665 GTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTR-RRCI---VEQYG 725

  Fly   649 NY-------------SRMDILIHSGGMQISYHSMLSLTGPIKGMARLPGL-NLTPTQIFFLVSAQ 699
            ||             ::.:.:..:||::.::.:............||||| ..|..||||:..|.
 Worm   726 NYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAH 790

  Fly   700 ELC------AESNYLGIDTNAPEFDNILGWLVAQGGSATEVFKCPSGSMINVQKTCNV 751
            ..|      |....:..|.::||...::| :::...:..:|:|||..:.:|....|.|
 Worm   791 FWCGKKKEAAAMQQVLTDEHSPEVFRVIG-VLSNMQAFADVYKCPRNAPVNPDHKCIV 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	142/715 (20%)
nep-11	NP_494538.1	M13	181..845	CDD:341056	142/715 (20%)