Protein Alignment Nepl16 and nep-9

DIOPT Version :9

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 708
• Identity: 124/708 - (17%)
• Similarity: 249/708 - (35%)
• Gaps: 177/708 - (25%)

  Fly   152 PPECSDPICEAVASSIQARLNWNKDPCTEFKKFSC-----------WRNTPNKNITNLIEMGNSQ 205
            |..|..|.|..:|..::|..:.....|.:|.|.:|           .|:...:...|.:..|..|
 Worm    61 PQFCESPQCIILAQELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAVNKLVRGFLQ 125

  Fly   206 KSVDSQMLYLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLG--GYLPV----GSVGPS 264
            :.         ::...:.|...:..:|..|.:.:.|::.:. ||..:.  |..||    ......
 Worm   126 RD---------ESTFTSESESAIKLIFGKCDELSRNTSYLD-IFKDIKKIGSWPVLEHNWKDSMF 180

  Fly   265 SIAPLIAKIYDLGPSPL----VDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSR 325
            ::..:|||:..||.:..    ::| ..|::|   |..:.:|...      |:.|..:........
 Worm   181 NLDDVIAKLVKLGSTDFGLFKLEL-RKLAFG---HFAVFVSSKQ------EQNIHQLEKTILGIL 235

  Fly   326 IRQGVPKLLADLIENFLPY--FVSYAQRVSEKDTIFEFIKDLNKLQVEHSRRGFWDSTVLYN--V 386
            ...|:.:...:|.::...|  |.::.:...:::|..|:              ..:..:::.|  :
 Worm   236 KANGIQQDRKELSDDLKDYSDFKNHLKEFYQEETYIEY--------------RLYAGSIVENLGI 286

  Fly   387 SSLQDLYPVLNWTLLIPQNWSGPIVVRNSDYL----KALEYFLTKYPTRVAHNSLLLLSALQILP 447
            |||.....:.:..|.:..:.:...::.||...    ..|...:.|.|.|...| .|:...:.::.
 Worm   287 SSLTTQMALKSTGLDVFNHVNQRTLITNSSLFFGEENNLGMIIQKTPKRTLAN-FLIFHFIDVMT 350

  Fly   448 RDYP-SPEVCTRSTMWALPELSSSLYIAQHSSEDLKD---------TTKRAEIIFKS---LKAHL 499
            .|.. :.:.|..:.:..||..|..:......:||.:|         .||..|:|..|   .|.||
 Worm   351 TDLANATKACKETLIDLLPRASIQVLSRNFVNEDAQDDMVKMAQDLKTKITEMIDNSPFFTKFHL 415

  Fly   500 --------KRAPSLKGAALVKLSALKIQSQTWEGFSNT--TDLLKSLQPL-NITSECWFQNILEI 553
                    |....:|...:|.....::..:.:|..:.|  ..:.:::|.| .:.||...:::
 Worm   416 VFDAEEQKKLIQKVKAIGIVTEYPQEVLDRDFERLNLTPSDSIYRTIQKLRRLRSEQLIEHL--- 477

  Fly   554 YKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGV 618
              ...|:|.|..:.|.:|            ||..::::.:...:|..|||:...|.|::...:|.
 Worm   478 --GGDLDPTDTRVWGSAH------------YDQTTNNLTIFAPIIDGPYFDTSYPNYVNQFLMGF 528

  Fly   619 SIAKEILRSI---------------------TKSFDEKAMRCVPHSVN---------------IF 647
            .:.:|:.||:                     .|.|||. ::|.....:               |.
 Worm   529 ILGRELGRSLDSVRIRKDEKGQTENWLKPESLKRFDEH-LKCWAEKYDKSADPLKSESKGIRQIE 592

  Fly   648 SNYSRMDILIHSGGMQISYHSMLSLTGPIKGMARLPGLNLTP-TQIFFLVSAQELC----AESNY 707
            ..|.:.::.....|.:.|:.:.:.|  .:|....|....:.. .::||.|.|...|    ..:::
 Worm   593 GRYIQNEMFADFIGHEASWRAFMKL--DVKNEEVLETFKVIKLRRMFFNVQALYFCRPPSGSTDW 655

  Fly   708 L--------------GIDTNAPEFDNILGWLVAQGGSATEVFKCPSGSMINVQKTCNV 751
            |              |...|.|:|              ...|:|.|...:|.|..|::
 Worm   656 LSYQEHHQHYSFRVNGAFKNMPQF--------------ALAFECASDDDMNPQNKCSM 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	117/680 (17%)
nep-9	NP_494531.2	M13	87..698	CDD:189000	117/679 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000