Protein Alignment Nepl16 and Nep5

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: XP_061503273.1
• Gene: Nep5 / 1273520
• VectorBaseID: AGAMI1_014349
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 886
• Identity: 170/886 - (19%)
• Similarity: 305/886 - (34%)
• Gaps: 343/886 - (38%)

  Fly   103 HKMAITSATLLVTTLLVASPILFLISTAPSPLPRDCYMDGDRCSPAVSAPPE-CSDPICEAVASS 166
            ||..:....|::..|.:|..::..:                     :..||| |....|...|::
Mosquito    54 HKSIVLFLLLVIFILTIAIIVIACL---------------------LHFPPEICHSADCLRSAAA 97

  Fly   167 IQARLNWNKDPCTEFKKFSC--WRN---TPN----------------KNITNLIEMGNSQKSVDS 210
            ::..::...|||.:|.:::|  |.:   .|:                :||.:.::..:|  ::|.
Mosquito    98 LKHSMDLTVDPCEDFYQYACGNWEDEHPRPDTYVSFDWFSERQAKILRNIRHYLQANSS--ALDP 160

  Fly   211 QMLYLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPV----------------- 258
            :.  :.|.:.|          :.:||    |.|.|.|:     ||.||
Mosquito   161 KP--VVQARTM----------YAACL----NLTAMDRL-----GYGPVFKYLKQFQLPPYPSLLN 204

  Fly   259 GSVGPSSI---------APLIAKIYDLGPSPL---VDLYHDLSYGRRPHILLIISGPSTSS---- 307
            .:.||:|.         ...:|||..|....:   :|:|.|..:  |.:..|::..|.:.|
Mosquito   205 VTEGPASATFQGYGFDWVKSLAKIKQLLGMDIFIGLDVYPDPRH--RDYNRLVLGTPESGSDLPF 267

  Fly   308 -TILERKIR------------------------------WMSPKAPPSRIRQGVPKLLAD----- 336
             |.:.|.||                              .:.|.....:...||.|||.:
Mosquito   268 NTDILRHIRRGRTRRKLMVSADDEADGESDGEEVEDADDEVGPLTAYKKFMIGVMKLLVNSTDPT 332

  Fly   337 -LIENFLPYFVSYAQRVSE-KDTIFEF------------IKDLNKLQVEHSRRGFWDSTVLYNVS 387
             .:|:|...|...|..|.: .|:|.:|            ::|...||          ..|.|.|:
Mosquito   333 IKVESFNAQFERAATIVVQFSDSISKFNREAENASRSTNVEDRLNLQ----------DIVYYTVA 387

  Fly   388 SLQDLY--------PVLNWTLLIPQNWSG-P----------IVVRNSD--YLKALEYFLTKYPTR 431
            .||::.        |:..|..|:...:.| |          |:..|:|  |||.|..:|...|
Mosquito   388 DLQNITDTHLAPKDPLPIWERLLASVFEGIPEAQLNLQDELILTSNADLLYLKLLVDYLAVTP-- 450

  Fly   432 VAH----------NSLLLLSALQI--LPRDY-----PSPEVCTRSTMWALPELSSSLYIAQH--- 476
            :||          ..|:|.:.|::  |..||     ||....:| |::....::..|.:|..
Mosquito   451 LAHIELYIWWTVVEELILHTTLEVRKLYYDYYKSIAPSDGFSSR-TLYCTGTVNRLLGMAVSYAI 514

  Fly   477 SSEDL-KDTTKRAEIIFKSLKAHLKRAPSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQP-- 538
            ||::. :||..|.:.:.:.::.      :.:|.         ::..||..:......|:..|.
Mosquito   515 SSDNFTRDTKPRVQDMLRYIRT------AFEGL---------VRDTTWMDWPTKQSTLRKSQAMR 564

  Fly   539 ---------------------LNITSECWFQNIL-EIYKKN--KL----EPNDISLNGGSHDAW- 574
                                 |.:......:|:: |:.:||  ||    :.:::|        |
Mosquito   565 SLIGFPDWILDHRELEQHYSGLQVNESTHLENMMQEVQRKNIIKLRRWRQKHELS--------WE 621

  Fly   575 AYPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRSITKSFDEKAM-- 637
            ..|.....|:....::|.:|::::..|:::..|.. |:|.::|..:..|    :|..||:...
Mosquito   622 TLPTNVNAFHTFQENAITIPIAILQYPFYHLGLEA-LNYGALGTILGHE----LTHGFDDSGRQF 681

  Fly   638 ------------RCVPHSVN----IFSNYSRMDI----------------LIHSGGMQISY--HS 668
                        |.|...||    ..|.|||..|                :..:||::.::  :.
Mosquito   682 DKDGNLAQWWTDRTVQEYVNRTKCFVSQYSRYYIPEADDYIDGLLTLGENIADNGGVREAFRAYQ 746

  Fly   669 MLSLTG---PIKGMARLPGL-NLTPTQIFFLVSAQELC------AESNYL------------GID 711
            :....|   |:     |||. :.|..|:||:......|      |...||            |:.
Mosquito   747 LYVKNGGKDPL-----LPGFEHYTHEQLFFISYGNIWCESHTQAAAKAYLDDSHCPGKFRLKGVL 806

  Fly   712 TNAPEFDNILGWLVAQGGSATEVFKCPSGSMINVQK-TCNV 751
            ||:|||              ::.|.|..|:.:|..| .|.:
Mosquito   807 TNSPEF--------------SQTFGCKPGTEMNPGKDKCRI 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	158/809 (20%)
Nep5	XP_061503273.1	None