Protein Alignment Nepl16 and ece2

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 721
• Identity: 149/721 - (20%)
• Similarity: 271/721 - (37%)
• Gaps: 174/721 - (24%)

  Fly   155 CSDPICEAVASSIQARLNWNKDPCTEFKKFSC--W-RNTPNKNITNLIEMGNSQKSVDSQMLYLF 216
            |....|.:||..|...|:...|||.:|.::||  | |..|   :.:.....|:..|:..|...:.
 Frog    95 CLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNP---LPDGRSRWNTFNSIWDQNQAIL 156

  Fly   217 QNKIMNGSFGI-------LHNLFESCLQQTTNSTVMHR----IFDSLGGYLPVGSVGPSSIAPLI 270
            ::.:.|.:|..       ....:.|||::.....:..:    :.:.:||:...|:....:...::
 Frog   157 KHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVL 221

  Fly   271 AKIYDLGPSPLVDLYHDLSYGRRPHILLIISGPSTS--STILERKIRWMSPKAPPSRIRQGVPKL 333
            ..:..             :|...|...:.:|..|.|  |.|::..   .|....|||........
 Frog   222 KTVSG-------------TYRATPFFSVFVSADSKSSNSNIIQVD---QSGLFLPSRDYYLNKTA 270

  Fly   334 LADLIENFLPYFVSYAQRVS--------EKDTIFEFIKDLNKLQVEHSRRGFWDSTVLYN---VS 387
            ...:::.:|.|.||..:.:.        :...|.||...|..|.|....|.  |...:||   :|
 Frog   271 NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERR--DEEKIYNRMTIS 333

  Fly   388 SLQDLYPVLNWT-----LLIP--QNWSGPIVVRNSDYLKALEYFLTKYPTRVAHNSLL------L 439
            .||.|.|..:|.     .|.|  .|.:.|:||...:||:.:...:......:.:|.|:      :
 Frog   334 ELQSLAPAFDWMDYLTFALSPLDLNDTEPVVVYGKEYLQQVSELVNNTDPMLLNNYLVWNLVQKM 398

  Fly   440 LSAL---------QILPRDYPSPEVCTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSL 495
            .|:|         ::|...|.:.:.||......|.....:|..|..|........|.::.|.:.:
 Frog   399 SSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQM 463

  Fly   496 KAHLKRAPSL------------KGAALVKLSAL-------------KIQSQTWEGFSNTTDLLKS 535
            .:.::.|..|            :.||..|..|:             |...:.::||
 Frog   464 ISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGF--------- 519

  Fly   536 LQPLNITSECWFQNILEIY--------KKNKLEPNDISLNGGSHDAWAY-PIVSTIFYDTLSHSI 591
                .::.:.:|||:|..|        ::.:..||        .:.|:. |.....:|....:.|
 Frog   520 ----EVSEDAFFQNMLNFYNFSAKLMAEQLRKPPN--------REQWSMTPQTVNAYYLPNKNEI 572

  Fly   592 VVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRSITKSFDEKA-------------------- 636
            |.|..::..|::....|..|::..:||.:..|    :|.:||::.
 Frog   573 VFPAGILQAPFYAPTHPKALNFGGIGVVMGHE----LTHAFDDQGREYDEDGNLRPWWQNSSLEA 633

  Fly   637 ----MRCVPHSVNIFS-NYSRM-------DILIHSGGMQISYH---SMLSLTGPIKGMARLPGLN 686
                ..|:.:..|.:: |..|:       :.:..:||::.:||   |.|...|..|   :|||:.
 Frog   634 FKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEK---QLPGVG 695

  Fly   687 LTPTQIFFLVSAQELCA----ESNYLGI--DTNAPEFDNILGWLVAQGGSATEVFKCPSGSMINV 745
            ||..|:||:..||..|:    ||::.|:  |.::|....::|.| :......|.|.||.|:.:|.
 Frog   696 LTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTL-SNSKDFAEHFNCPKGTPMNP 759

  Fly   746 QKTCNV 751
            .|.|:|
 Frog   760 GKHCDV 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	141/697 (20%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	141/697 (20%)