Protein Alignment fd96Cb and HCM1

DIOPT Version :9

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_009991.2
• Gene: HCM1 / 850429
• SGDID: S000000661
• Length: 564
• Species: Saccharomyces cerevisiae
• Alignment Length: 316
• Identity: 82/316 - (25%)
• Similarity: 122/316 - (38%)
• Gaps: 96/316 - (30%)

  Fly    12 QKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPR 76
            :||||||.:|..:||:.|.:..|.||:||.:|...||:|::....||||:|||||.||.|||..:
Yeast   108 KKPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEK 172

  Fly    77 NVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNW--------KLAAAANTEMVT 133
            :..  |||.:|.:.|.|...|..|.  .|...| ||...:||..:        :|....:.|...
Yeast   173 SCD--GKGHFWEVRPGAETKFFKGE--NRGYEF-VKDSLQDIGKYFEIDSTLDELEQVESGEGND 232

  Fly   134 HYLDDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARPKRAFTIESLMAPDP 198
            ...|::..:.|...|:.  .:..|:|           |||  .|:||...|:       |...:.
Yeast   233 DLPDEEEREEAGKFPSI--EIQLNSS-----------PIL--RVSQLHHIPQ-------LKTDNS 275

  Fly   199 ASTPNEGLVPM------EYGSPDAVALEKPPF--------------------------------- 224
            ...|:|.|..|      :..:.|::   :||:
Yeast   276 VLNPHENLESMRNMIENDVNNIDSL---EPPYVMKKYHTSLGLPSLVNAKDHFQAGVKNNNITQA 337

  Fly   225 ----NLPFNFNELAAQYQLYFPSFFYNGQYGNIPCYQKTPPLFHN-------GPLP 269
                .||....:....::.||.||..|        ::...||..|       .|||
Yeast   338 NRFNTLPITSAKSPQNFRKYFTSFNSN--------FEDLSPLRSNVGAGSLLDPLP 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	40/87 (46%)
		Alpha_kinase	106..>194	CDD:295997	19/95 (20%)
HCM1	NP_009991.2	COG5025	20..564	CDD:227358	82/316 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm46522
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.040