Protein Alignment fd96Cb and FOXN1

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: XP_011523660.1
• Gene: FOXN1 / 8456
• HGNCID: 12765
• Length: 649
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 73/271 - (26%)
• Similarity: 105/271 - (38%)
• Gaps: 64/271 - (23%)

  Fly    13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVP-R 76
            ||.|||..|..||:.:|....||:||||.|:.:.||:::.....|:||:|||||.|.||.||. :
Human   272 KPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENK 336

  Fly    77 NVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEMVTHYLDDQLT 141
            :.:.:.||..|.|:|...|                 ::::::..||..            |....
Human   337 SGSSSRKGCLWALNPAKID-----------------KMQEELQKWKRK------------DPIAV 372

  Fly   142 QMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARP--------KRAFTIESLMAPDP 198
            :.:.|.|.....::.:......||....||  |......|.||        ....::.....|.|
Human   373 RKSMAKPEELDSLIGDKREKLGSPLLGCPP--PGLSGSGPIRPLAPPAGLSPPLHSLHPAPGPIP 435

  Fly   199 ASTPNEGLV----PMEYG------SPDAVALEKPP---FNLPFNFNELAAQYQLYFPSFFYNGQY 250
            ...|.:.|:    |..||      || .:|...||   |..|....||.||          .|..
Human   436 GKNPLQDLLMGHTPSCYGQTYLHLSP-GLAPPGPPQPLFPQPDGHLELRAQ----------PGTP 489

  Fly   251 GNIPCYQKTPP 261
            .:.|....|||
Human   490 QDSPLPAHTPP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	37/97 (38%)
FOXN1	XP_011523660.1	FH_FOXN1	271..367	CDD:410830	39/111 (35%)