DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Cb and foxf1

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001039226.1	Gene:	foxf1 / 734087	XenbaseID:	XB-GENE-478922	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	99/332 - (29%)
Similarity:	136/332 - (40%)	Gaps:	96/332 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPR 76
            :|||||||:|..|||..||.:.|.|||||:|:..:|||:|.:.|.|:||:|||||.|:||||:|:
Frog    53 EKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPK 117

  Fly    77 NVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVK-QLEKDI-------------SNWKLAAAA 127
            .:.:.|||.|||:.|.:..|||.||..||.:.||.| |..|.:             ..:....|:
Frog   118 GLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHIPETYSFQGAS 182

  Fly   128 NT--------------EMVTHYLDDQLTQMAFA-DPARH-----GH----VLANASAAQMSPYKA 168
            .|              .|:..:|...:..|..: .|..|     ||    ....:|....|.:.:
Frog   183 GTIACPPNSLSLDSGIGMMNGHLPSNVDGMGLSGHPVSHIAANGGHSYMGSCTGSSGGDYSHHDS 247

  Fly   169 TPPIL-------PTTVTQLPARPKRAFTIESLMAPDPASTP----------NEGLVPMEYG---- 212
            ..|:|       |.:|...||         |..||. ||||          |....|:...
Frog   248 GSPLLGGGGVMEPHSVYSSPA---------SAWAPS-ASTPYIKQQPLSPCNSAANPLSSSLSSH 302

  Fly   213 SPDAVAL-------------------EKPPFN----LPFNFNELAAQYQLYFPSFFYNGQYGNIP 254
            |.|...|                   :.|..|    ..|:||.:|:.........:|:.|.|
Frog   303 SLDQSYLHQNSHNTASELQGIPRYHSQSPSMNDRKEFVFSFNAMASSSMHSGSGSYYHQQVG--- 364

  Fly   255 CYQKTPP 261
             ||...|
Frog   365 -YQDIKP 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	49/87 (56%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	23/132 (17%)
foxf1	NP_001039226.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51
		Forkhead	53..139	CDD:365978	47/85 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..255		4/18 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	283..306		3/22 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910