Protein Alignment fd96Cb and FOXL2

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_075555.1
• Gene: FOXL2 / 668
• HGNCID: 1092
• Length: 376
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 97/296 - (32%)
• Similarity: 120/296 - (40%)
• Gaps: 91/296 - (30%)

  Fly    12 QKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPR 76
            |||||||::|.||||..|.::.|.||.||::|:.:||||.||.:.||||:|||||.|:|||||||
Human    53 QKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPR 117

  Fly    77 NVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFR------------------------------- 110
            ......||:||||.|...||||.|:..|||:..|
Human   118 EGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAG 182

  Fly   111 ---------VKQLEKDISN--W--------------KLAAAANTEMVTHYLDDQLTQMAFADPAR 150
                     .|.|:....|  |              ::||||......         .|.|.|..
Human   183 ADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAA---------AAAAGPGS 238

  Fly   151 HGHV-----LANASAAQMSPY-----KATPPILPTTVTQL---PARP---------KRAFTIESL 193
            .|..     || ..||...||     .|.||.:..:...|   ||.|         ..|..:.:.
Human   239 PGAAAVVKGLA-GPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAA 302

  Fly   194 MAPDPASTPNEGLVPMEYG--SPDAVALEKPPFNLP 227
            .||.|| .|:.|......|  ||.:.|...||...|
Human   303 AAPPPA-PPHHGAAAPPPGQLSPASPATAAPPAPAP 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	57/97 (59%)
FOXL2	NP_075555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		97/296 (33%)
		FH_FOXL2	54..142	CDD:410802	52/87 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..342		18/63 (29%)