DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Cb and foxd4l1.1

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001016928.1	Gene:	foxd4l1.1 / 549682	XenbaseID:	XB-GENE-479247	Length:	352	Species:	Xenopus tropicalis

Alignment Length:	255	Identity:	91/255 - (35%)
Similarity:	118/255 - (46%)	Gaps:	72/255 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRN 77
            |||||||:|..|||:.||.:.|.||.|..||..:||:|:.....||||:|||||.||||||:||.
Frog    97 KPPYSYIALITMAILQSPHKKLTLSGICDFISSKFPYYKDKFPAWQNSIRHNLSLNDCFIKIPRE 161

  Fly    78 VTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLE--KD----------------------I 118
            ....|||:||||.|.:.|||:|||.|||||||:..|.|  ||                      :
Frog   162 PGNPGKGNYWTLDPASEDMFDNGSFLRRRKRFKRHQQEFFKDGLVMYNPLPYYRPYSTIQPQQVL 226

  Fly   119 SNWKLAAAA---NTEMVTHY--LDDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILPTTVT 178
            ....:|..|   |..|.||.  ..|...::.:.|...|...  .|..|...|.|
Frog   227 QQTPVACMAIPENLTMPTHLSPYPDIKRKVPYPDQGVHRGF--EALDADNHPNK----------- 278

  Fly   179 QLPARPKRAFTIESLM----APDPA-STPNEGLVPMEYGSPDAVALEKPPFNLPFNFNEL 233
               ::.|.:|:||::|    .|:|: ||                      ||..:|:|.|
Frog   279 ---SQSKCSFSIENIMRKPKEPEPSFST----------------------FNPHWNYNHL 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	51/87 (59%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	25/116 (22%)
foxd4l1.1	NP_001016928.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..92
		Forkhead	97..183	CDD:278670	50/85 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940