Protein Alignment fd96Cb and FOXB2

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001013757.1
• Gene: FOXB2 / 442425
• HGNCID: 23315
• Length: 432
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 114/336 - (33%)
• Similarity: 145/336 - (43%)
• Gaps: 110/336 - (32%)

  Fly     1 MPRPLKMSYGDQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNL 65
            ||||.|.||.||||||||||||||||.||.:::||||:||:|||::||:||::||:|||||||||
Human     1 MPRPGKSSYSDQKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNL 65

  Fly    66 SFNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTE 130
            ||||||||:||...:.||||:|.|||...|||||||.|||||||:|.:.:.
Human    66 SFNDCFIKIPRRPDQPGKGSFWALHPDCGDMFENGSFLRRRKRFKVLRADH-------------- 116

  Fly   131 MVTHYLDDQLTQMAFADPA--------------RHGHVLANASAAQMSP---------------- 165
              ||...........|.|.              .|.|..|:.......|
Human   117 --THLHAGSTKSAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHHPPQPPPPPPPPPPHMVHY 179

  Fly   166 YKATPPILPTTVTQLPARPKRAFTIESLMAPDPASTPNEGLVPMEYGSPDAVAL----------- 219
            :...||..|.....||::|.:        .|...|.|.:...|.:.....|||.
Human   180 FHQQPPTAPQPPPHLPSQPPQ--------QPPQQSQPQQPSHPGKMQEAAAVAAAAAAAAAAAVG 236

  Fly   220 ------EKPPFNL-------------------PFNFNEL-----------------AAQYQLYFP 242
                  :.||:.|                   ||....:                 :..:.|.:|
Human   237 SVGRLSQFPPYGLGSAAAAAAAAAASTSGFKHPFAIENIIGRDYKGVLQAGGLPLASVMHHLGYP 301

  Fly   243 SFFYNGQYGNI 253
               ..||.||:
Human   302 ---VPGQLGNV 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	80/108 (74%)
FOXB2	NP_001013757.1	FH_FOXB2	1..110	CDD:410817	80/108 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..220		17/109 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..432