DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Cb and FOXD4L4

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_954714.2	Gene:	FOXD4L4 / 349334	HGNCID:	23762	Length:	416	Species:	Homo sapiens

Alignment Length:	191	Identity:	76/191 - (39%)
Similarity:	97/191 - (50%)	Gaps:	46/191 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRN 77
            |||||||:|..|||:.:|.:.|.||.|..||..:||:||:....||||:|||||.||||:|:||.
Human   108 KPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPRE 172

  Fly    78 VTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEMVTHYLDDQLTQ 142
            ....|||:||:|.|.:.|||:|||.|||||||:..||.....            :.|
Human   173 PGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAH------------LPH-------- 217

  Fly   143 MAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARPKRAFTIESLMAPDPASTPN 203
             .|..||.|        ||..:|:       |..:...||.|:          |.|.:.||
Human   218 -PFPLPAAH--------AALHNPH-------PGPLLGAPAPPQ----------PVPGAYPN 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	49/87 (56%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	18/87 (21%)
FOXD4L4	NP_954714.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..105
		Forkhead	108..194	CDD:278670	48/85 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.870