DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fd96Cb and foxk2a

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001184186.1	Gene:	foxk2a / 324141	ZFINID:	ZDB-GENE-030131-2861	Length:	544	Species:	Danio rerio

Alignment Length:	219	Identity:	69/219 - (31%)
Similarity:	98/219 - (44%)	Gaps:	42/219 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVP 75
            |.||||||..|...||..:|.:.|.|:.||..|...:|:||...:.||||:|||||.|..||||.
Zfish   202 DSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVA 266

  Fly    76 RNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKR----FRVKQLEKDISNWKLAAAANTEMVTHYL 136
            |:..:.||||:|.:.|.:.....:.:..:||.|    ||..                       |
Zfish   267 RSQEEPGKGSFWRIDPSSEGKLMDQAFRKRRPRGVPCFRTP-----------------------L 308

  Fly   137 DDQLTQMAFADPARHGHVLANASAAQM--SPYKATP-PILPTTVTQLPARPKRAFTIESLMAPDP 198
            ....::.|.|.|...|.:.|::|..|.  |..:.:| |:.|........:||.|...||...
Zfish   309 GPLSSRSAPASPTHTGVLSAHSSGVQTPDSSREGSPLPLEPEPSAAAAPQPKLAVIQESCFT--- 370

  Fly   199 ASTPNEGLVPMEYGSPDAVALEKP 222
            .:||         |||..:|:::|
Zfish   371 QNTP---------GSPVLIAVQQP 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	39/87 (45%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	21/94 (22%)
foxk2a	NP_001184186.1	FHA	16..105	CDD:238017
foxk2a	NP_001184186.1	Forkhead	204..290	CDD:278670	39/85 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940