Protein Alignment fd96Cb and FOXA3

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_004488.2
• Gene: FOXA3 / 3171
• HGNCID: 5023
• Length: 350
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 105/280 - (37%)
• Similarity: 138/280 - (49%)
• Gaps: 72/280 - (25%)

  Fly     1 MPRPLKMSYGDQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNL 65
            ||:..:......|||||||||..|||..:|.::|.|||||::|||.||:||:|.|:||||:||:|
Human   105 MPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSL 169

  Fly    66 SFNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTE 130
            ||||||:||.|:..|.||||||.|||.:.:|||||..|||:|||:   ||:.:......||..|
Human   170 SFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFK---LEEKVKKGGSGAATTT- 230

  Fly   131 MVTHYLDDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARPKRAFTIESLMA 195
                               |:|    ..|||..:    ||   ..|||..|..|.        .|
Human   231 -------------------RNG----TGSAASTT----TP---AATVTSPPQPPP--------PA 257

  Fly   196 PDPASTPNEGLVPMEYGSPDA-----VALEKP---------PFNLPFNFNELAAQ-------YQL 239
            |:|.:...|.:..::.|||.:     ..||.|         .||.||:.|.|.::       ..:
Human   258 PEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDV 322

  Fly   240 YF---------PSFFYNGQY 250
            .|         |..:|.|.|
Human   323 GFGGYGAEGGEPGVYYQGLY 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	66/108 (61%)
FOXA3	NP_004488.2	FH_FOXA3	115..216	CDD:410814	65/103 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..276		20/97 (21%)