DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Cb and foxd2

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_571346.2	Gene:	foxd2 / 30525	ZFINID:	ZDB-GENE-980605-6	Length:	369	Species:	Danio rerio

Alignment Length:	245	Identity:	91/245 - (37%)
Similarity:	124/245 - (50%)	Gaps:	41/245 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRN 77
            |||||||:|..|||:.||::.|.||||..||.::||:||:....||||:|||||.||||:|:||.
Zfish    95 KPPYSYIALITMAILQSPKKRLTLSEICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE 159

  Fly    78 VTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDIS----------------NWKLAAA 126
            ....|||:||||.|.:.|||:|||.|||||||:..|..:.:.                |:.|...
Zfish   160 PGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRHQTNEILREAGGFLPGFGYGPYGYNYGLQLQ 224

  Fly   127 ---ANTEMVTHY----LDDQLTQMAFADPAR-----H------GHVLANASAAQMSPYKATPPIL 173
               |:.....|:    ...|.|..|...|:.     |      |..|......|:||  ..|.:.
Zfish   225 NFHAHHPYHPHHPGSAFPFQNTHCALPTPSSIFSTPHSLPSFLGTELRKPFYPQLSP--TLPGLA 287

  Fly   174 P-TTVTQLPARPKRAFTIESLMAPDPASTPNEGLVPMEYGSPDAVALEKP 222
            | .|.|..|:||  :|:|::::.  .||:|.........|....:|:..|
Zfish   288 PLKTDTNGPSRP--SFSIDNIIG--AASSPASPYTTQPAGQAQILAMLTP 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	52/87 (60%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	28/122 (23%)
foxd2	NP_571346.2	Forkhead	95..181	CDD:278670	51/85 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.900