Protein Alignment fd96Cb and Foxo3

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001099865.1
• Gene: Foxo3 / 294515
• RGDID: 1309196
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 289
• Identity: 71/289 - (24%)
• Similarity: 114/289 - (39%)
• Gaps: 89/289 - (30%)

  Fly    17 SYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYR-----KNTQKWQNSLRHNLSFNDCFIKVPR 76
            ||..|...||..||.:.|.||:||.:::...|:::     .::..|:||:|||||.:..|::|..
  Rat   160 SYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQN 224

  Fly    77 NVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEMVTHYLDDQLT 141
            ..|  ||.|:|.::|   |..::|...|||      .:..|.||                  :.|
  Rat   225 EGT--GKSSWWIINP---DGGKSGKAPRRR------AVSMDNSN------------------KYT 260

  Fly   142 QMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARP-------------------KRA 187
            :       ..|......:|.|.:|..|...  |:.:::.|..|                   ..|
  Rat   261 K-------SRGRAAKKKAALQAAPESADDS--PSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNA 316

  Fly   188 FTIESLMAPDPAST------PNEG-LVPMEYGSPDAV--ALEKP-PFNLP--------FNFNELA 234
            .|:...::|..|||      .::| |.||.|.|..::  ::.|| ...||        .|.|:..
  Rat   317 STVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGL 381

  Fly   235 AQYQLYFPSFFYNGQYGNI--PCYQKTPP 261
            |:..:       :....||  |..|.:||
  Rat   382 AENLM-------DDLLDNIALPPSQASPP 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	34/97 (35%)
Foxo3	NP_001099865.1	FH_FOXO3	156..238	CDD:410835	29/82 (35%)
		FOXO_KIX_bdg	431..510	CDD:465228
		FOXO-TAD	605..643	CDD:435506