Protein Alignment fd96Cb and FOXC2

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_005242.1
• Gene: FOXC2 / 2303
• HGNCID: 3801
• Length: 501
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 110/299 - (36%)
• Similarity: 144/299 - (48%)
• Gaps: 68/299 - (22%)

  Fly    13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRN 77
            |||||||:|..|||.::|::.:.|:.||:||||:|||||:|.|.||||:|||||.|:||:||||:
Human    72 KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD 136

  Fly    78 VTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWK---------LAAAANTEMVT 133
            ..|.||||||||.|.:::||||||.||||:||:    :||:|..|         ..||:.....|
Human   137 DKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFK----KKDVSKEKEERAHLKEPPPAASKGAPAT 197

  Fly   134 HYLDDQ--------LTQMAFADPA----RHGHVLANASAAQMSPYKA--TPPILPTTVTQLPARP 184
            .:|.|.        :.:...|.||    .....|:..||.|.||..|  ||...|.  ..||...
Human   198 PHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPD--GSLPEHH 260

  Fly   185 KRA------FTIESLM-----------AP---------DPASTPNEGLVPMEYGSPDAVALEKPP 223
            ..|      |::|::|           :|         .|.:.|.....|..||.|.|..||.
Human   261 AAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEA-- 323

  Fly   224 FNLPFNFNELAAQYQLYFPSF-FYNGQYGNIPCYQKTPP 261
                    ..|..||....:. .|.|  ...|.:...||
Human   324 --------GAAGGYQCSMRAMSLYTG--AERPAHMCVPP 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	63/96 (66%)
FOXC2	NP_005242.1	FH_FOXC1	67..159	CDD:410818	55/86 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..208		11/44 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..268		12/37 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..420