Protein Alignment fd96Cb and Foxk1

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_951031.2
• Gene: Foxk1 / 17425
• MGIID: 1347488
• Length: 719
• Species: Mus musculus
• Alignment Length: 246
• Identity: 73/246 - (29%)
• Similarity: 97/246 - (39%)
• Gaps: 49/246 - (19%)

  Fly    11 DQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVP 75
            :.||||||..|...||..:..|.|.||.||..|...:|:||...:.||||:|||||.|..|||||
Mouse   289 ESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSLNRYFIKVP 353

  Fly    76 RNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKR----FRVKQLEKDISNWKLAAAANTEMVTHYL 136
            |:..:.||||:|.:.|.:.......:..:||:|    ||..                       .
Mouse   354 RSQEEPGKGSFWRIDPASEAKLVEQAFRKRRQRGVSCFRTP-----------------------F 395

  Fly   137 DDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLPARPKRAFTIESLMAPDPAST 201
            ....::.|.|.|...|.:...:|..|      ||..|....:.:|..|.        :....||.
Mouse   396 GPLSSRSAPASPTHPGLMSPRSSGLQ------TPECLSREGSPIPHDPD--------LGSKLASV 446

  Fly   202 PNEGLVPMEYGSP---DAVALEKPPFNLPFNFNELAAQYQLYFPSFFYNGQ 249
            |.........|||   ..|.:..||  .|.|   |.|:...|.|:.....|
Mouse   447 PEYRYSQSAPGSPVSAQPVIMAVPP--RPSN---LVAKPVAYMPASIVTSQ 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	44/102 (43%)
Foxk1	NP_951031.2	Interaction with SIN3A and SIN3B. /evidence=ECO:0000269|PubMed:10620510, ECO:0000269|PubMed:22476904	2..40
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..67
		Required for interaction with FOXO4 and MEF2C. /evidence=ECO:0000269|PubMed:22956541	81..406		47/139 (34%)
		FHA	89..191	CDD:469597
		FH_FOXK1	289..389	CDD:410828	44/99 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	399..443		11/57 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	665..719