DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Cb and Foxd2

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_032619.1	Gene:	Foxd2 / 17301	MGIID:	1347471	Length:	492	Species:	Mus musculus

Alignment Length:	246	Identity:	93/246 - (37%)
Similarity:	117/246 - (47%)	Gaps:	56/246 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRN 77
            |||||||:|..|||:.||::.|.||||..||..:||:||:....||||:|||||.||||:|:||.
Mouse   129 KPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE 193

  Fly    78 VTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQL---------EKDISNWKLAAAANTEMVT 133
            ....|||:||||.|.:.|||:|||.|||||||:.:.|         ..::.....||||.
Mouse   194 PGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAG----- 253

  Fly   134 HYLDDQLTQMAFA-------------------------DPARHGHVLANASAA--QMS--PYKAT 169
               |......:||                         .|..|.|..|.|:.|  |:|  |.:|.
Mouse   254 ---DPGAFLSSFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHPHAFAFAATAPCQLSVPPGRAA 315

  Fly   170 PPILPTTVTQLPARPKRAFTIESLMAPDPASTPNEGLVPMEYGSPDAVALE 220
            .|  |      |..|..:....:..||.||..|..|  |...|.|..:..|
Mouse   316 AP--P------PGPPTASVFASAASAPAPAPAPGSG--PSPAGLPAFLGAE 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	52/87 (60%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	26/125 (21%)
Foxd2	NP_032619.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..125
		Forkhead	129..215	CDD:278670	51/85 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..344		12/44 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	394..441
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.960