DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd96Cb and Foxa2

DIOPT Version :9

Sequence 1:NP_524496.1 Gene:fd96Cb / 43011 FlyBaseID:FBgn0004898 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_001277994.1 Gene:Foxa2 / 15376 MGIID:1347476 Length:465 Species:Mus musculus


Alignment Length:292 Identity:110/292 - (37%)
Similarity:157/292 - (53%) Gaps:42/292 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 PRPLKMSYGDQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLS 66
            |:..:.||...|||||||||..|||..||.::|.|||||::|||.|||||:|.|:||||:||:||
Mouse   154 PKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLS 218

  Fly    67 FNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEM 131
            |||||:||||:..|.||||:|||||.:.:|||||..|||:|||:   .||.::..:.|.||::..
Mouse   219 FNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK---CEKQLALKEAAGAASSGG 280

  Fly   132 VTHYLDDQLTQMAFADPARHGHVLANAS---AAQMSPYKATPPILPTT---VTQLPARPKRAFTI 190
            .......|.:|      |:.|....:||   |...||:.:..|.....   :::|...|..|   
Mouse   281 KKTAPGSQASQ------AQLGEAAGSASETPAGTESPHSSASPCQEHKRGGLSELKGAPASA--- 336

  Fly   191 ESLMAPDPASTPNE---------------GLVPMEYGSPDAVALEKPPFNLPFNFNELAAQYQLY 240
              |..|:||.:|.:               ||.|..:..|:    ....||.||:.|.|.:..|.:
Mouse   337 --LSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPE----HHYAFNHPFSINNLMSSEQQH 395

  Fly   241 FPSFFYNGQYG-NIPCYQKTP--PLFHNGPLP 269
            ..|..::..:. ::..|::..  |..:..|:|
Mouse   396 HHSHHHHQPHKMDLKAYEQVMHYPGGYGSPMP 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd96CbNP_524496.1 FH 13..101 CDD:214627 61/87 (70%)
Alpha_kinase 106..>194 CDD:295997 21/93 (23%)
Foxa2NP_001277994.1 Forkhead_N 23..164 CDD:254796 3/9 (33%)
FH 165..253 CDD:214627 61/87 (70%)
DUF4799 <224..319 CDD:292674 40/103 (39%)
HNF_C 381..454 CDD:286443 10/47 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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