Protein Alignment fd96Cb and Foxa2

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001277994.1
• Gene: Foxa2 / 15376
• MGIID: 1347476
• Length: 465
• Species: Mus musculus
• Alignment Length: 292
• Identity: 110/292 - (37%)
• Similarity: 157/292 - (53%)
• Gaps: 42/292 - (14%)

  Fly     2 PRPLKMSYGDQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLS 66
            |:..:.||...|||||||||..|||..||.::|.|||||::|||.|||||:|.|:||||:||:||
Mouse   154 PKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLS 218

  Fly    67 FNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWKLAAAANTEM 131
            |||||:||||:..|.||||:|||||.:.:|||||..|||:|||:   .||.::..:.|.||::..
Mouse   219 FNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK---CEKQLALKEAAGAASSGG 280

  Fly   132 VTHYLDDQLTQMAFADPARHGHVLANAS---AAQMSPYKATPPILPTT---VTQLPARPKRAFTI 190
            .......|.:|      |:.|....:||   |...||:.:..|.....   :::|...|..|
Mouse   281 KKTAPGSQASQ------AQLGEAAGSASETPAGTESPHSSASPCQEHKRGGLSELKGAPASA--- 336

  Fly   191 ESLMAPDPASTPNE---------------GLVPMEYGSPDAVALEKPPFNLPFNFNELAAQYQLY 240
              |..|:||.:|.:               ||.|..:..|:    ....||.||:.|.|.:..|.:
Mouse   337 --LSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPE----HHYAFNHPFSINNLMSSEQQH 395

  Fly   241 FPSFFYNGQYG-NIPCYQKTP--PLFHNGPLP 269
            ..|..::..:. ::..|::..  |..:..|:|
Mouse   396 HHSHHHHQPHKMDLKAYEQVMHYPGGYGSPMP 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	70/107 (65%)
Foxa2	NP_001277994.1	Forkhead_N	23..164	CDD:369872	3/9 (33%)
		FH_FOXA2	163..264	CDD:410813	68/103 (66%)
		PRK07764	<266..>354	CDD:236090	21/98 (21%)
		HNF_C	380..454	CDD:430552	11/48 (23%)