Protein Alignment fd96Cb and FOXN4

DIOPT Version :10

• Sequence 1: NP_524496.1
• Gene: fd96Cb / 43011
• FlyBaseID: FBgn0004898
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: XP_011536224.1
• Gene: FOXN4 / 121643
• HGNCID: 21399
• Length: 518
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 79/297 - (26%)
• Similarity: 122/297 - (41%)
• Gaps: 81/297 - (27%)

  Fly     2 PRPLKMSYGDQ--------KPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQ 58
            |:|....:..|        ||.|||..|.|||:.:|....||:||||.|:.:.||:::.....|:
Human   175 PQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWK 239

  Fly    59 NSLRHNLSFNDCFIKVPRNVT-KAGKGSYWTLHPMAFDMFENGSLLRRRKRFRVKQLEKDISNWK 122
            ||:|||||.|.||.||...:: .:.||..|.|: :|                |:.::|:::..||
Human   240 NSVRHNLSLNKCFEKVENKMSGSSRKGCLWALN-LA----------------RIDKMEEEMHKWK 287

  Fly   123 ---LAAAANTEMVTHYLDDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILP-----TT--- 176
               |||               ...:.|:|.....::::...:...|.|...|..|     ||
Human   288 RKDLAA---------------IHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAV 337

  Fly   177 ------VTQLPARPKRAFTIESL-----------MAPD---PASTPNEGLVPMEYGSPDAVALEK 221
                  |:|||.:|....:::|:           :|||   ||.||....:|....||    |..
Human   338 AHGCLAVSQLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSP----LPH 398

  Fly   222 PPF-NLPFNF----NELAAQYQLYFPSFFYNGQYGNI 253
            |.. ..|.:|    .::..:.....||.......||:
Human   399 PAMGRAPVDFINISTDMNTEVDALDPSIMDFALQGNL 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH_FOX	1..110	CDD:469596	40/116 (34%)
FOXN4	XP_011536224.1	PABP-1234	<56..219	CDD:130689	15/43 (35%)
		FH_FOXN4	189..294	CDD:410831	44/136 (32%)
		FAM75	318..>398	CDD:464237	23/83 (28%)