DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fd96Cb and foxk2

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001135634.1	Gene:	foxk2 / 100216193	XenbaseID:	XB-GENE-483520	Length:	645	Species:	Xenopus tropicalis

Alignment Length:	226	Identity:	68/226 - (30%)
Similarity:	97/226 - (42%)	Gaps:	46/226 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DQKPPYSYISLTAMAIIHSPQRLLPLSEIYRFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVP 75
            |.||||||..|...||..:|.:.|.|:.||..|...:|:||...:.||||:|||||.|..|||||
Frog   217 DSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVP 281

  Fly    76 RNVTKAGKGSYWTLHPMAFDMFENGSLLRRRKR----FRVKQLEKDISNWKLAAAANTEMVTHYL 136
            |:..:.||||:|.:.|.:.......:..:||.|    ||..                       |
Frog   282 RSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTP-----------------------L 323

  Fly   137 DDQLTQMAFADPARHGHVLANASAAQMSPYKATPPILPTTVTQLP-------ARPKRAFTIESLM 194
            ....::.|.|.|...|.:.|::|..|      ||..|....:.:|       .:||.|...|:..
Frog   324 GPLSSRSAPASPNHAGVLSAHSSGLQ------TPESLSREGSPIPMEPEPSAIQPKLAVIQEARF 382

  Fly   195 APDPASTP---NEGLVPMEYGSPDAVALEKP 222
            |.....:|   .:.|:.::...|..:   ||
Frog   383 AQSAPGSPLSSQQVLIAVQRQLPQTI---KP 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	40/87 (46%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	20/98 (20%)
foxk2	NP_001135634.1	FHA	10..117	CDD:238017
foxk2	NP_001135634.1	Forkhead	218..304	CDD:365978	40/85 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030