DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Cb and foxc1a

DIOPT Version :9

Sequence 1:	NP_524496.1	Gene:	fd96Cb / 43011	FlyBaseID:	FBgn0004898	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_571803.1	Gene:	foxc1a / 100148408	ZFINID:	ZDB-GENE-010302-1	Length:	476	Species:	Danio rerio

Alignment Length:	242	Identity:	94/242 - (38%)
Similarity:	127/242 - (52%)	Gaps:	49/242 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRPLKM---------------SYGDQ----------KPPYSYISLTAMAIIHSPQRLLPLSEIY 40
            ||.|:.|               :||..          |||||||:|..|||.:||.:.:.|:.||
Zfish    37 MPAPMTMYSHAAHDQYPASMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNSPDKKVTLNGIY 101

  Fly    41 RFIMDQFPFYRKNTQKWQNSLRHNLSFNDCFIKVPRNVTKAGKGSYWTLHPMAFDMFENGSLLRR 105
            :|||::|||||.|.|.||||:|||||.|:||:||||:..|.||||||||.|.:::||||||.|||
Zfish   102 QFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRR 166

  Fly   106 RKRFRVKQLEKDISNWKLAAAANTEMVTHYLDDQLTQMAFADPARHGHVLANASAAQMSPYKATP 170
            |:||:.|...||..: :....|.:........:|...:..:.|.|...:......:  :|.:|..
Zfish   167 RRRFKKKDAMKDKED-RGVKEAPSRQAQPQAREQEQSVPGSQPVRIQDIKTENGTS--TPPQAVS 228

  Fly   171 PILPTTVTQLPARPKRAFTIESLMAPDPASTPNEGLVPMEYGSPDAV 217
            |.|.|.       ||    |||   ||.:|:       |..|||.::
Zfish   229 PTLSTV-------PK----IES---PDSSSS-------MSSGSPHSI 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Cb	NP_524496.1	FH	13..101	CDD:214627	56/87 (64%)
fd96Cb	NP_524496.1	Alpha_kinase	106..>194	CDD:295997	20/87 (23%)
foxc1a	NP_571803.1	Forkhead	74..160	CDD:278670	54/85 (64%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	169..271		26/110 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	284..303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010