DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and foxk2b

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_001922856.1	Gene:	foxk2b / 798356	ZFINID:	ZDB-GENE-030131-5310	Length:	597	Species:	Danio rerio

Alignment Length:	361	Identity:	96/361 - (26%)
Similarity:	150/361 - (41%)	Gaps:	62/361 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVP 75
            :.||||||..|...||..:|:|.|.|:.||..||..:||||...:.||||:|||||.|..|||||
Zfish   209 DSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVP 273

  Fly    76 RRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNRFFFTTRNGG 140
            |..:.||||::|.:.|.:.......:..:||.|      ........|..|::.:.......:|.
Zfish   274 RSQEEPGKGSFWRIDPSSEGKLVEQAFRKRRPR------GVPCFRTPLGPLSSRSAPASPNHSGV 332

  Fly   141 SAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGP--GVPLPHVMP--ASMSGADHT-NLADMGLT 200
            .:||.|.:...::.:....|:|..:.  |.|:.|  .|.:..|.|  |.:.....| |.....:|
Zfish   333 LSAHSSGVQTPDSLSREGSPVPMESE--PVSVPPPAAVAVAAVQPKLAVIQETRFTQNTTASPIT 395

  Fly   201 NLPALTSSEIEGPLS----------LRPKRSFT--------------IESLITPDKPEHPSEDED 241
            ..|.|.:  ::.||:          ..|..|.|              |.::........|.|:.|
Zfish   396 TQPVLIA--VQRPLTQNMKPVTYAVAAPVSSSTSAQPLMQTVHVVHQIPAVAVSTVKTEPRENGD 458

  Fly   242 DEDDRVDIDVVECSGISRYPTTPAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLHY------ 300
            .::.:|.::.|  .||        |.....:|:|..:|.....|:.|:......|...:
Zfish   459 YDELKVKVEAV--PGI--------AHGSIGTANRVIQTSAAATPLQTVTIVQQAPLGQHQLPIKT 513

  Fly   301 --ATGANVAGLPASGIPNSPTTYELAISHPLFMMAA 334
              ..|.:|..: |:.|.:...|    :|.||.::||
Zfish   514 ITQNGTHVVPI-ATAIQSQANT----VSSPLHLLAA 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	43/87 (49%)
foxk2b	XP_001922856.1	FHA	17..109	CDD:238017
foxk2b	XP_001922856.1	Forkhead	211..297	CDD:278670	43/85 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940