Protein Alignment fd96Ca and FOXL2

DIOPT Version :10

• Sequence 1: NP_524495.1
• Gene: fd96Ca / 43010
• FlyBaseID: FBgn0004897
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_075555.1
• Gene: FOXL2 / 668
• HGNCID: 1092
• Length: 376
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 114/400 - (28%)
• Similarity: 155/400 - (38%)
• Gaps: 140/400 - (35%)

  Fly     2 PRPSRESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLS 66
            |.|:      |||||||::|.||||..|.||.|.||.||::|..:||:|.||.:.||||:|||||
Human    49 PDPA------QKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLS 107

  Fly    67 FNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFK-------LH-KNDKDLLNEEL 123
            .|:|||||||......||.||.|.|...||||.|: .|||:|.|       .| :..|.|...
Human   108 LNECFIKVPREGGGERKGNYWTLDPACEDMFEKGN-YRRRRRMKRPFRPPPAHFQPGKGLFGA-- 169

  Fly   124 TALANLNRFFFTTRNGGSA-------------AHMSPLD------MNNAAAMRLDPLPRSTAHMP 169
                           ||:|             .:::|..      :||:.     |||:..:.||
Human   170 ---------------GGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSW-----PLPQPPSPMP 214

  Fly   170 -----------------NSLGPGVPLPHVMPASMSG-----ADHTNLADMGLTNLPALTSS--EI 210
                             .:.|||.|....:...::|     ..:|.:..|.|.  |.:.:|  .:
Human   215 YASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALP--PGVVNSYNGL 277

  Fly   211 EGPLSLRPKRSFTIESLITPDKPEHPSEDEDDEDDRVDIDVVECSGISRYPTTPAASEEYMSASR 275
            .||.:             .|..|.||                       :| .|.|...:.:|:
Human   278 GGPPA-------------APPPPPHP-----------------------HP-HPHAHHLHAAAA- 304

  Fly   276 SSRTEDPLPPMHTINAGAHVPFLHYATGANVAGLPASGIPNSPTTYELAISHPLFMMAA----PI 336
                ..|.||.|    ||..|    ..|......||:..|.:|.    ..|.|....|.    .:
Human   305 ----PPPAPPHH----GAAAP----PPGQLSPASPATAAPPAPA----PTSAPGLQFACARQPEL 353

  Fly   337 ANMHNIYYNN 346
            |.||..|:::
Human   354 AMMHCSYWDH 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_524495.1	FH_FOX	1..110	CDD:469596	60/107 (56%)
FOXL2	NP_075555.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		2/9 (22%)
		FH_FOXL2	54..142	CDD:410802	52/87 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..342		23/119 (19%)