DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and FOXD4L6

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001078945.1	Gene:	FOXD4L6 / 653404	HGNCID:	31986	Length:	417	Species:	Homo sapiens

Alignment Length:	187	Identity:	84/187 - (44%)
Similarity:	101/187 - (54%)	Gaps:	39/187 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SRESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFND 69
            |.::....|||||||:|..|||..:|.|.|.||.|..||:.||||||:....||||:|||||.||
Human   100 SEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLND 164

  Fly    70 CFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNRFFF 134
            ||:|:||.|..||||.||:|.|.:.|||:|||.||||||||.|         :||..|:|
Human   165 CFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRH---------QLTPGAHL----- 215

  Fly   135 TTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGP--GVPLPHVMPASMSGA 189
                    .|..||           |...:..|.|:. ||  |.|.|   |..:.||
Human   216 --------PHPFPL-----------PAAHAALHNPHP-GPLLGAPAP---PQPVPGA 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	54/87 (62%)
FOXD4L6	NP_001078945.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..105		1/4 (25%)
		Forkhead	108..194	CDD:278670	53/85 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910