DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and foxa1

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_989419.1	Gene:	foxa1 / 395059	XenbaseID:	XB-GENE-487352	Length:	428	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	107/298 - (35%)
Similarity:	147/298 - (49%)	Gaps:	49/298 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDC 70
            |.||...|||||||||..|||..:|.|||.||:||::|.|.|.|||:|.||||||:||:||||||
Frog   151 RRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFLYYRQNQQRWQNSIRHSLSFNDC 215

  Fly    71 FIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKND---------KDLLNEELTAL 126
            |:||.|.||:||||:||.|||.:.:|||||..|||:||||..|..         ||:....
Frog   216 FVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQQGGKGSQDGRKDVSGPS---- 276

  Fly   127 ANLNRFFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADH 191
            :.|:|.     :|.|:...|...|:|.::.     |:|..|..::   |...|.|.......:.|
Frog   277 SPLHRV-----HGKSSQMDSSSSMSNPSSS-----PQSLEHNGSN---GEMKPQVAAGPSPLSSH 328

  Fly   192 TNLADMGLTNLPALTSSEIEGPLSLRPKRSFTIESLITPDKPEHPSEDEDDEDDRVDIDVVECSG 256
            .|.:...|.:   .|...::|.........|:|.:|::..:.:|          ::|....| ..
Frog   329 QNHSTHSLAH---ETHIHLKGDPHYSFNHPFSINNLMSSSEQQH----------KLDFKAYE-QA 379

  Fly   257 ISRY-------PTTPAASEEYMSASRSSRTEDPLPPMH 287
            :.:|       |..|..|..  .|.|.|.....|.|.:
Frog   380 LQQYSSYSGGLPGMPLGSPS--MAGRGSIEPSALEPTY 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	60/87 (69%)
foxa1	NP_989419.1	Forkhead_N	17..157	CDD:369872	3/5 (60%)
		FH	158..246	CDD:214627	60/87 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	257..337		18/96 (19%)
		HNF_C	354..417	CDD:370449	15/75 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910