DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and FoxK

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	97/369 - (26%)
Similarity:	136/369 - (36%)	Gaps:	101/369 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSRESYG-EQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQR-WQNSLRHNLS 66
            ||..||. .:||||||..|...||.::|:|.|.||.||.||...:|||||.|.: ||||:|||||
  Fly   443 PSTASYNHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLS 507

  Fly    67 FNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNR 131
            .|..||||.|..|.||||::|.:.|.:.....:.|..:||:|
  Fly   508 LNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQR----------------------- 549

  Fly   132 FFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADHTNLAD 196
                    .|.....|..|..:|       |.|.:||.||                 .:.:.|.|
  Fly   550 --------SSQGFRPPYGMPRSA-------PVSPSHMDNS-----------------RESSPLQD 582

  Fly   197 MGLTNLPALTSSEIEGPLSLRPKRSFTIESLITPDKPEHPSEDEDDEDDRVDIDVVECSGISRYP 261
            :.|.:.|......:|       :|:...| :|...:..|..:.:..:.             .:..
  Fly   583 IVLQSAPGSPGMSLE-------QRAADPE-IIYNSQNAHQQQQQQQQQ-------------QQQQ 626

  Fly   262 TTPAASEEYMSASRSSRTEDPLPPMHTIN--AGAHVPFLHYATGANVAGLPASGIPNSPTTYELA 324
            |....|.:|.|.|          |.:..|  :|...|..|....|...|....|:...     ||
  Fly   627 TLSNNSNQYSSGS----------PYYVTNQSSGVATPQTHVEGSAASGGGGGGGVGAL-----LA 676

  Fly   325 ISHPLFMMAAPIANMHNIYYNNVTLVAPAQQYRSPEVQNRIDND 368
            :.....|...  |:.|.::...    |.|||..|..:...:..|
  Fly   677 LKRNHVMGGG--ASQHTLHQQQ----AVAQQQHSEIIYEELPTD 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	46/88 (52%)
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	46/86 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445551
Domainoid	1	1.000	104	1.000	Domainoid score	I1720
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm46522
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.870