DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and foxk1

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_956196.1	Gene:	foxk1 / 334470	ZFINID:	ZDB-GENE-030131-6402	Length:	639	Species:	Danio rerio

Alignment Length:	393	Identity:	99/393 - (25%)
Similarity:	151/393 - (38%)	Gaps:	111/393 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVP 75
            |.||||||..|...||.|:.::.|.||.||..||..:||||...:.||||:|||||.|..|||||
Zfish   256 ESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSLNRYFIKVP 320

  Fly    76 RRPDRPGKGAYWALHPQAFDMFENGSLLRRRKR----FK--------------------LHKNDK 116
            |..:.||||::|.:.|.:.......:..:||:|    |:                    |..:..
Zfish   321 RSQEEPGKGSFWRVDPSSEAKLVEQAFRKRRQRGVSCFRTPFGPLSSRSAPASPTHSGLLSPHSS 385

  Fly   117 DLLNEEL---------------TALANLNRFFFTTRNGGSAAHMSPLDM----NNAAAMRLDPLP 162
            .|...|.               :.||::..:.::....||.....|:.|    .::||     :.
Zfish   386 GLQTPECLSREGSPVSHEHDFGSKLASVPEYRYSQSAPGSPVSAQPVIMAVPSQSSAA-----IS 445

  Fly   163 RSTAHMPNSL---------------GPGVPLPHVMPASMSGADHTNLADMGLTNLPALTSSEIEG 212
            :..|:||:.:               .|.|.:..|:..|.|..:...||:         |||...|
Zfish   446 KPVAYMPSIISSSQASGQAIHVVQQAPAVTMVRVVTTSTSSPNGYILAN---------TSSSGPG 501

  Fly   213 PLSLRPKRSFTIESLITPDKPEHPSEDEDDEDDRVDIDVVECSGISRYPTTPAASEEYMSASRSS 277
            .|...|:.:.                   ||...|...|::..| |...:.....:.|....:|:
Zfish   502 DLHGDPRGAL-------------------DEMPLVGSRVIQAVG-SHIASANRGQQSYTVVQQSA 546

  Fly   278 RTEDPLPPMHTINAGAHVPFLHYATGANVAGLPASGIPNSPTTYELAISHPLFMMAAPIANMHNI 342
                    :|      |:|....|.....| ||.:.||.|    ..|:::||.::||..:....:
Zfish   547 --------IH------HLPVQTIAQNGKHA-LPVTSIPTS----AYALTNPLQILAAQASTSPPV 592

  Fly   343 YYN 345
            ..|
Zfish   593 LVN 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	43/87 (49%)
foxk1	NP_956196.1	FHA	23..165	CDD:224630
		FHA	68..152	CDD:238017
		Forkhead	258..344	CDD:278670	43/85 (51%)
		Cyto_heme_lyase	370..>465	CDD:279589	14/99 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940