DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and foxk2a

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001184186.1	Gene:	foxk2a / 324141	ZFINID:	ZDB-GENE-030131-2861	Length:	544	Species:	Danio rerio

Alignment Length:	352	Identity:	95/352 - (26%)
Similarity:	137/352 - (38%)	Gaps:	80/352 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVP 75
            :.||||||..|...||..:|:|.|.|:.||..||..:||||...:.||||:|||||.|..||||.
Zfish   202 DSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVA 266

  Fly    76 RRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNRFFFTTRNGG 140
            |..:.||||::|.:.|.:.....:.:..:||.|      ........|..|::.:.....|..|.
Zfish   267 RSQEEPGKGSFWRIDPSSEGKLMDQAFRKRRPR------GVPCFRTPLGPLSSRSAPASPTHTGV 325

  Fly   141 SAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADHTNLA-------DMG 198
            .:||.|.:                  ..|:|...|.|||.....|.:.|....||       ...
Zfish   326 LSAHSSGV------------------QTPDSSREGSPLPLEPEPSAAAAPQPKLAVIQESCFTQN 372

  Fly   199 LTNLPALTSSEIEGPL--SLRPKRSFTIESLITPDKPEHP--------------------SEDED 241
            ....|.|.:  ::.||  ||:|. ||   |:.||.....|                    :|.::
Zfish   373 TPGSPVLIA--VQQPLQQSLKPV-SF---SVATPASSAAPQPVMQTLHLLHQIPAACVFRAEQQN 431

  Fly   242 DEDDRVDIDVVECSGISRYPTTPAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLHYATGANV 306
            .:...|.:.|.....::..|  .|:|......:.:.|.:..||.......|.||
Zfish   432 GDAQEVKVTVEPVPAVAAAP--GASSRVLQPLAVAPRGQHQLPVKPITQNGTHV----------- 483

  Fly   307 AGLPASGIPNSPTTYELAISHPLFMMA 333
               .|:.|..|.:|     :.||.|:|
Zfish   484 ---AAAAIQGSAST-----ASPLHMLA 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	42/87 (48%)
foxk2a	NP_001184186.1	FHA	16..105	CDD:238017
foxk2a	NP_001184186.1	Forkhead	204..290	CDD:278670	42/85 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940