DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and foxa2

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_571024.1	Gene:	foxa2 / 30126	ZFINID:	ZDB-GENE-980526-404	Length:	409	Species:	Danio rerio

Alignment Length:	348	Identity:	114/348 - (32%)
Similarity:	162/348 - (46%)	Gaps:	102/348 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PRPSRESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLS 66
            |:..|.||...|||||||||..|||..||.|||.||:||::|.|.||:||:|.||||||:||:||
Zfish   140 PKTYRRSYTHAKPPYSYISLITMAIQQSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLS 204

  Fly    67 FNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKN-DKDLLNEELTALANLN 130
            |||||:||||.||:||||::|.|||.:.:|||||..|||:||||..|. .||...:.....:|.:
Zfish   205 FNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCDKKLSKDPSRKTSEGGSNSS 269

  Fly   131 RFFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPH-VMPASMS----GAD 190
            .   .:.||..:.|      :|:::   :.|.||.:.|.:  |.|:...| ..|.|.:    ...
Zfish   270 S---ESCNGNESPH------SNSSS---NELKRSLSDMKS--GQGLSPDHAASPTSQAQHLLAQH 320

  Fly   191 HTNLADMGLTNLPALTSSEIEGPLSLRPK------RSFTIESLITPDKPEHPSEDEDDEDDRVDI 249
            |:.||..|                .|:|:      ..|:|.:|::.::..|          ::|:
Zfish   321 HSVLAHEG----------------HLKPEHHYSFNHPFSINNLMSSEQQHH----------KMDL 359

  Fly   250 DVVECSGISRYPTTPAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLHYATGANVAGLPASGI 314
            ...|                                          ..:||..|:.:||..:.|.
Zfish   360 KTYE------------------------------------------QVMHYGYGSPMAGTLSMGS 382

  Fly   315 P------NSPTT--YELAISHPL 329
            .      :||.|  |:...|.|:
Zfish   383 MASKAGLDSPDTSYYQGVYSRPI 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	61/87 (70%)
foxa2	NP_571024.1	Forkhead_N	18..150	CDD:254796	4/9 (44%)
		FH	151..239	CDD:214627	61/87 (70%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	250..315		17/78 (22%)
		HNF_C	340..398	CDD:286443	15/109 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910