DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and fkh2

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_596764.1	Gene:	fkh2 / 2539703	PomBaseID:	SPBC16G5.15c	Length:	642	Species:	Schizosaccharomyces pombe

Alignment Length:	359	Identity:	95/359 - (26%)
Similarity:	133/359 - (37%)	Gaps:	117/359 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YGE-QKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFI 72
            ||: :||||||..:.|.||.||.|.|:.||:||.:|:..:||||.....||||:|||||.|..|.
pombe   218 YGDNKKPPYSYSVMIAQAILSSSECMMTLSNIYSWISTHYPYYRTTKSGWQNSIRHNLSLNKAFR 282

  Fly    73 KVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNRFFFTTR 137
            ||||:....|||..|::.|:    |....:.:.||                           |.|
pombe   283 KVPRKSGEQGKGMKWSIVPE----FREEFIAKTRK---------------------------TPR 316

  Fly   138 NGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADHTNLADMGLTNL 202
            ....::                |:|........|  |.:|:| ::|            .|..|::
pombe   317 KRSPSS----------------PVPLLAKKREGS--PSLPIP-ILP------------KMKDTSI 350

  Fly   203 PALTSSEIEGPLSLRPKRSFTIESLITPDKPE---HPSEDEDDEDDRVDIDVVECSGISRYPT-T 263
            ||           ..|..|.|.....||..|:   .||..|...:::         .:..|.| |
pombe   351 PA-----------AEPASSTTSARDQTPSTPKDVGSPSTAETSAEEK---------QMETYKTPT 395

  Fly   264 PAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLHYATGANVAG---LPASGIPNSPTTYELAI 325
            .||..:.:|      |.|                  ||..||.|.   ..|.|.|...:||..:.
pombe   396 HAALSDIIS------THD------------------YALDANSASQTKKAAFGSPIGSSTYPTSS 436

  Fly   326 SHPLFMMAAPIANMHNIYYNNVTLVAPAQQYRSP 359
            ..|.:...| :.|.|:  :..|........||:|
pombe   437 PAPFWKYVA-VPNPHD--WPQVGSYDTISPYRNP 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	43/87 (49%)
fkh2	NP_596764.1	COG5025	6..622	CDD:227358	95/359 (26%)
		FHA	81..185	CDD:238017
		Forkhead	223..308	CDD:278670	43/88 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	104	1.000	Domainoid score	I1720
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm47009
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940