Protein Alignment fd96Ca and Foxa2

DIOPT Version :10

• Sequence 1: NP_524495.1
• Gene: fd96Ca / 43010
• FlyBaseID: FBgn0004897
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001386014.1
• Gene: Foxa2 / 25099
• RGDID: 2808
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 113/342 - (33%)
• Similarity: 153/342 - (44%)
• Gaps: 48/342 - (14%)

  Fly     2 PRPSRESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLS 66
            |:..|.||...|||||||||..|||..||.|||.||:||::|.|.||:||:|.||||||:||:||
  Rat   154 PKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLS 218

  Fly    67 FNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNR 131
            |||||:||||.||:||||::|.|||.:.:|||||..|||:||||.   :|.|..:|
  Rat   219 FNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKC---EKQLALKE--------- 271

  Fly   132 FFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADHTNLAD 196
                ....||...........|:.::|.....|.:..|    .|...||...:.........|::
  Rat   272 ----AAGAGSGGGKKTAPGTQASQVQLGEAAGSASETP----AGTESPHSSASPCQEHKRGGLSE 328

  Fly   197 MGLTNLPALTSSEIEGPLSLRPKRSFTIESLITPDKPEHPSEDEDDEDDRVDIDVVECSGISRYP 261
              |...||...|..|...|...::......|:.|..|..|.|.....:.....:
  Rat   329 --LKGTPASALSPPEPAPSPGQQQQAAAHLLVPPHHPGLPPEAHLKPEHHYAFN----------- 380

  Fly   262 TTPAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLHYATG--------------ANVAGLPAS 312
             .|.:....||:.:...........|.::...:...:||..|              .|.|||.||
  Rat   381 -HPFSINNLMSSEQQHHHSHHHHQPHKMDLKTYEQVMHYPGGYGSPMPGSLAMGPVTNKAGLDAS 444

  Fly   313 GIPNSPTTYELAISHPL 329
            .:....:.|:...|.|:
  Rat   445 PLAADTSYYQGVYSRPI 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_524495.1	FH_FOX	1..110	CDD:469596	71/107 (66%)
Foxa2	NP_001386014.1	Forkhead_N	23..164	CDD:369872	4/9 (44%)
		FH_FOXA2	163..264	CDD:410813	69/103 (67%)
		COG5025	<164..380	CDD:227358	93/237 (39%)
		HNF_C	380..454	CDD:430552	13/85 (15%)