Protein Alignment fd96Ca and FOXC2

DIOPT Version :9

• Sequence 1: NP_001287516.1
• Gene: fd96Ca / 43010
• FlyBaseID: FBgn0004897
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_005242.1
• Gene: FOXC2 / 2303
• HGNCID: 3801
• Length: 501
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 130/426 - (30%)
• Similarity: 171/426 - (40%)
• Gaps: 120/426 - (28%)

  Fly    13 KPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVPRR 77
            |||||||:|..|||.::|||.:.|:.||:||.||||:||:|.|.||||:|||||.|:||:||||.
Human    72 KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD 136

  Fly    78 PDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNRFFFTTRNGGSA 142
            ..:||||:||.|.|.:::||||||.||||:|||  |.|   :::|....|:|.........|..|
Human   137 DKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFK--KKD---VSKEKEERAHLKEPPPAASKGAPA 196

  Fly   143 A-HM--SPLDMNNAAAMR----------------------LDPLPRSTAHMPNSLGPGVPLPHVM 182
            . |:  :|.:......::                      |...|||.|..|.. .|...||...
Human   197 TPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAG-SPDGSLPEHH 260

  Fly   183 PASMSGADHTNLADMGLTNLPALTSSEIEGPLSLRPKR--------------------------- 220
            .|:.:|     |....:.|:..|.:|...|.||....|
Human   261 AAAPNG-----LPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQG 320

  Fly   221 -----------SFTIESLIT-PDKPEH----PSEDEDDEDDRVDIDVVECSGISRYPTTP----- 264
                       |....||.| .::|.|    |:.||...|        ..||    ||:|
Human   321 LEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSD--------HPSG----PTSPLSALN 373

  Fly   265 -AASEEYMSASRSSRTE------------DPLP-PMHTINAGAHVPFLHYATGANVAG--LPASG 313
             ||.:|...|:.....:            .|.| |..|...|        |..|..|.  |..||
Human   374 LAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPG--------AAAAQAASWYLNHSG 430

  Fly   314 IPNSPTTYELAISHPLFMMAAPIANMHNIYYNNVTL 349
            ..|....:..|.....|.....:.|.|.:...|.||
Human   431 DLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTL 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	55/87 (63%)
FOXC2	NP_005242.1	FH	72..160	CDD:214627	55/87 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..208		12/45 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..268		11/41 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..420		7/44 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910