DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and FOXI1

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_036320.2	Gene:	FOXI1 / 2299	HGNCID:	3815	Length:	378	Species:	Homo sapiens

Alignment Length:	326	Identity:	107/326 - (32%)
Similarity:	146/326 - (44%)	Gaps:	73/326 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRPSRESYGE-QKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHN 64
            :|.||:|...: .:|||||.:|.||||..:|:|.|.||.||:::.|.||:|.|:...||||:|||
Human   110 LPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHN 174

  Fly    65 LSFNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANL 129
            ||.||||.||||..|.||||.||.|.|....||:||:..|:|||    |:|   ::....:|| |
Human   175 LSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR----KSD---VSSSTASLA-L 231

  Fly   130 NRFFFTTRNG---GSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADH 191
            .:    |.:.   .|.....|.|:.:.|:      |..|...|.. .|..|        .|||..
Human   232 EK----TESSLPVDSPKTTEPQDILDGAS------PGGTTSSPEK-RPSPP--------PSGAPC 277

  Fly   192 TNLADMGLTNLPALTSSEIEGPLSLRPKRSFTIESLITPDKPEHPSEDEDDEDDRVDIDVVECSG 256
            .|   ..|:::.|..|.           .|.|...|:||.....||       |:...:.:..:.
Human   278 LN---SFLSSMTAYVSG-----------GSPTSHPLVTPGLSPEPS-------DKTGQNSLTFNS 321

  Fly   257 ISRYPTTPAASEEYMSASRSSRTEDPLPPMHT--INAGAHV-----PFLHYATGANVAGL--PAS 312
            .|  |.|        :.|..|...|...||.|  ::.|..|     |  |:....|.:|:  |..
Human   322 FS--PLT--------NLSNHSGGGDWANPMPTNMLSYGGSVLSQFSP--HFYNSVNTSGVLYPRE 374

  Fly   313 G 313
            |
Human   375 G 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	51/87 (59%)
FOXI1	NP_036320.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		FH	123..211	CDD:214627	51/87 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..278		24/96 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910