back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fd96Ca and FOXG1

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_005240.3	Gene:	FOXG1 / 2290	HGNCID:	3811	Length:	489	Species:	Homo sapiens

Alignment Length:	336	Identity:	107/336 - (31%)
Similarity:	140/336 - (41%)	Gaps:	74/336 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLSFNDCFIKVPR 76
            :|||:||.:|..|||..||||.|.|:.||:||...|||||:|.|.||||:|||||.|.||:||||
Human   180 EKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPR 244

  Fly    77 RPDRPGKGAYWALHPQAFDMFENGSL--LRRR---KRFKL-HKNDKDLLNEELTALANLNRFFFT 135
            ..|.||||.||.|.|.:.|:|..|:.  ||||   .|.|| .|....|.:..||         |.
Human   245 HYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLT---------FM 300

  Fly   136 TRNGGSAAHMSP------------LDMN-NAAAMRLDPLPRSTAHMPNSLG--------PGVPLP 179
            .|.|.....|||            |..| ..:|....|:|.|:....||||        .|:.:.
Human   301 DRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVD 365

  Fly   180 HVMPASMSGADHTNLADMGLTNLPALTSSEIEGPLSLRPKRSFTIESLITPDKPEHPSEDEDDED 244
            .::...:..|.|...|.....::|...|....|..||.|.....:....:...|..|
Human   366 RLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVP-------- 422

  Fly   245 DRVDIDVVECSGISRYPTTPAASEEYMSASRSSRTEDP--------------LPPMHT-INAGAH 294
                           :|:..:.|...|||..:|.:..|              ||...| ::.|..
Human   423 ---------------HPSMTSQSSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLS 472

  Fly   295 VPFLHYATGAN 305
            ..|.|...|::
Human   473 DYFTHQNQGSS 483

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.