DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and Foxd2

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_032619.1	Gene:	Foxd2 / 17301	MGIID:	1347471	Length:	492	Species:	Mus musculus

Alignment Length:	272	Identity:	100/272 - (36%)
Similarity:	127/272 - (46%)	Gaps:	46/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PRPSRESYGEQ------KPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNS 60
            |.|...|.|..      |||||||:|..|||..||:|.|.||:|.:||:.||||||:....||||
Mouse   112 PGPGPPSGGAATRSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNS 176

  Fly    61 LRHNLSFNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKL----------HKND 115
            :|||||.||||:|:||.|..||||.||.|.|::.|||:|||.||||||||.          |.:.
Mouse   177 IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHP 241

  Fly   116 KDLLNEELTALANLNRFFFTTRNGGSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLG------- 173
            :.||.....|..:...|..:....|:..:...|.:....|....|.|....| |::..
Mouse   242 ELLLRGGAAAAGDPGAFLSSFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPH-PHAFAFAATAPC 305

  Fly   174 -------------PGVPLPHVMPASMSGADHTNLADMGLT--NLPALTSSEIEG------PLSLR 217
                         ||.|...|..::.|..........|.:  .|||...:|: |      |.||.
Mouse   306 QLSVPPGRAAAPPPGPPTASVFASAASAPAPAPAPGSGPSPAGLPAFLGAEL-GCAKAFYPASLS 369

  Fly   218 PKRSFTIESLIT 229
            |..:.|..||.|
Mouse   370 PPAAGTAASLST 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	55/87 (63%)
Foxd2	NP_032619.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..125		4/12 (33%)
		Forkhead	129..215	CDD:278670	54/85 (64%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..344		5/34 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	394..441
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910