DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd96Ca and Foxa3

DIOPT Version :9

Sequence 1:	NP_001287516.1	Gene:	fd96Ca / 43010	FlyBaseID:	FBgn0004897	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_032286.1	Gene:	Foxa3 / 15377	MGIID:	1347477	Length:	353	Species:	Mus musculus

Alignment Length:	245	Identity:	103/245 - (42%)
Similarity:	131/245 - (53%)	Gaps:	42/245 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRPSRESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNL 65
            |.:..|......|||||||||..|||..:|.|||.||:||::|.|.|||||:|.||||||:||:|
Mouse   107 MAKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSL 171

  Fly    66 SFNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLN 130
            ||||||:||.|.||:||||:||||||.:.:|||||..|||:|||||.:..|           ..|
Mouse   172 SFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAK-----------KGN 225

  Fly   131 RFFFTTRNG--GSAAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGPGVPLPHVMPASMSGADHTN 193
            .....:|||  |||...:   ...|.|:.....|:.|   |:.           |.:.||.|...
Mouse   226 SATSASRNGTAGSATSAT---TTAATAVTSPAQPQPT---PSE-----------PEAQSGDDVGG 273

  Fly   194 LADMGL--TNLPALTSSEIEGPLSLRP----KRSFTIESLI-----TPDK 232
            | |...  ::.|..:..|:.|.|.|..    ...|:|.:|:     ||.|
Mouse   274 L-DCASPPSSTPYFSGLELPGELKLDAPYNFNHPFSINNLMSEQTSTPSK 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_001287516.1	FH	13..101	CDD:214627	62/87 (71%)
Foxa3	NP_032286.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	52..83
		FH	119..207	CDD:214627	62/87 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..287		20/96 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910