Protein Alignment fd96Ca and Foxa2

DIOPT Version :10

• Sequence 1: NP_524495.1
• Gene: fd96Ca / 43010
• FlyBaseID: FBgn0004897
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001277994.1
• Gene: Foxa2 / 15376
• MGIID: 1347476
• Length: 465
• Species: Mus musculus
• Alignment Length: 355
• Identity: 120/355 - (33%)
• Similarity: 163/355 - (45%)
• Gaps: 74/355 - (20%)

  Fly     2 PRPSRESYGEQKPPYSYISLTAMAIWSSPEKMLPLSDIYKFITDRFPYYRKNTQRWQNSLRHNLS 66
            |:..|.||...|||||||||..|||..||.|||.||:||::|.|.||:||:|.||||||:||:||
Mouse   154 PKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLS 218

  Fly    67 FNDCFIKVPRRPDRPGKGAYWALHPQAFDMFENGSLLRRRKRFKLHKNDKDLLNEELTALANLNR 131
            |||||:||||.||:||||::|.|||.:.:|||||..|||:||||.   :|.|..:|....|:
Mouse   219 FNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKC---EKQLALKEAAGAAS--- 277

  Fly   132 FFFTTRNGGS----AAHMSPLDMNNAAAMRLDPLPRSTAHMPNSLGP-------------GVP-- 177
                  :||.    .:..|...:..||....: .|..|....:|..|             |.|
Mouse   278 ------SGGKKTAPGSQASQAQLGEAAGSASE-TPAGTESPHSSASPCQEHKRGGLSELKGAPAS 335

  Fly   178 -LPHVMPASMSGADHTNLAD-MGLTNLPALTSSEIEGPLSLRPK------RSFTIESLITPDKPE 234
             |....||...|......|. :|..:.|.|...     ..|:|:      ..|:|.:|::.::..
Mouse   336 ALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPE-----AHLKPEHHYAFNHPFSINNLMSSEQQH 395

  Fly   235 HPSEDEDDEDDRVDIDVVECSGISRYPTTPAASEEYMSASRSSRTEDPLPPMHTINAGAHVPFLH 299
            |.|. ...:..::|:...|  .:..||      ..|.|....|....|:
Mouse   396 HHSH-HHHQPHKMDLKAYE--QVMHYP------GGYGSPMPGSLAMGPV---------------- 435

  Fly   300 YATGANVAGLPASGIPNSPTTYELAISHPL 329
                .|.|||.||.:....:.|:...|.|:
Mouse   436 ----TNKAGLDASPLAADTSYYQGVYSRPI 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd96Ca	NP_524495.1	FH_FOX	1..110	CDD:469596	71/107 (66%)
Foxa2	NP_001277994.1	Forkhead_N	23..164	CDD:369872	4/9 (44%)
		FH_FOXA2	163..264	CDD:410813	69/103 (67%)
		PRK07764	<266..>354	CDD:236090	18/97 (19%)
		HNF_C	380..454	CDD:430552	19/102 (19%)