Protein Alignment CG11920 and RPF1

DIOPT Version :10

• Sequence 1: NP_651335.2
• Gene: CG11920 / 43009
• FlyBaseID: FBgn0039274
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: NP_079341.2
• Gene: RPF1 / 80135
• HGNCID: 30350
• Length: 349
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 96/298 - (32%)
• Similarity: 157/298 - (52%)
• Gaps: 33/298 - (11%)

  Fly     7 RQRREYLYNK----ALTERLKSKQKIQETVVKSINENKAIGSKNVKKSL--TAYKSLKYADEGVD 65
            :|||..::.:    ...|:|.:|:|:::       |.:|:|.|...|.:  |......|.:..||
Human    60 KQRRHLMFTRWKQQQRKEKLAAKKKLKK-------EREALGDKAPPKPVPKTIDNQRVYDETTVD 117

  Fly    66 DRTVNDE---YHYAGCE---------DPKIMLTTSHNPSSRLKMFMKELRLIIPNAQQMNRGNYQ 118
            .   |||   |..|..|         .|||::|||..|..|.....::|..:|||:....|....
Human   118 P---NDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLA 179

  Fly   119 LTTLMHACRANNVTDFLIVHEHRGIPDSLVVCHLPYGPTAFFNISDVVMRHDIPDIG-HMSEQKP 182
            |..::..|.|.:.||.::::|.|..|:.|::.|||.||||.|.:|.|.:|.:|...| ..:|..|
Human   180 LKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIP 244

  Fly   183 HLIFNNFKTPIGLRTVKILKHLFP-VPKENSQRVMSFLNHNDSIIFRHHQYKY-VNKELELTEVG 245
            .:|.|||.|.:|....::...||| .|:...::|.:|.|..|.|.||.|:|.: ..|::.:.|:|
Human   245 EIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELG 309

  Fly   246 PRFSLKLYQIKLGTLENIKAADTEWINRP-YMNTSQKR 282
            |||:|||..::.||.:: |..:.||:::| .|:||:::
Human   310 PRFTLKLRSLQKGTFDS-KYGEYEWVHKPREMDTSRRK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11920	NP_651335.2	Brix	84..250	CDD:214879	59/168 (35%)
RPF1	NP_079341.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..105		12/51 (24%)
		Brix	145..314	CDD:214879	59/168 (35%)
		RNA-binding. /evidence=ECO:0000250	303..320		8/16 (50%)