DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shams and gxylt2

DIOPT Version :9

Sequence 1:	NP_001097911.1	Gene:	shams / 43008	FlyBaseID:	FBgn0039273	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001103670.1	Gene:	gxylt2 / 567541	ZFINID:	ZDB-GENE-070424-64	Length:	441	Species:	Danio rerio

Alignment Length:	329	Identity:	154/329 - (46%)
Similarity:	211/329 - (64%)	Gaps:	25/329 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 QTGKP---------PLYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFTEDGKGDEFREKL 97
            :.|:|         .:::.||:||.|:.|||.|:|||:||:..:  :||.||.|:...::|....
Zfish    94 EVGRPRSKVTLAEDVMHLAVVACGNRLDETLNMVKSALLFSMKK--IKFHIFAEEDLAEQFERGF 156

  Fly    98 TDWRDIKPFTFDFEILPLKFPSGNEVEWRNLFKPCAAQRLFLPSLLTHVDSLLYVDTDILFLSPI 162
            :.|.......|.:.|.|:.|..||..||:.|||||||||||||.:|..||||||||||:|||.|:
Zfish   157 SQWPQTLSSRFHYSIYPITFSVGNADEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPM 221

  Fly   163 SDIWRFFKKFNETQMSALTPEHENENIGWYNRFARHPFYGRLGVNSGVMLMNLTRMRE------- 220
            .|||:|.|.||.||::|:.||||...||||:||||||:||..|||||||||||||:|.
Zfish   222 DDIWKFLKAFNSTQLAAMAPEHEIPKIGWYSRFARHPYYGVTGVNSGVMLMNLTRIRNTLFRNSM 286

  Fly   221 ----MKWEQHIVSIHKEYKLRIIWGDQDIINILFYYHPDKLYIMPCEYNYRPDHCMYMSICNMS- 280
                :.||..:..::::||..|.|||||::||:|:|:|:.|||.||::|||||||||.|.|..:
Zfish   287 IASGLSWENLLHPLYQKYKNHITWGDQDLLNIIFHYNPECLYIFPCQWNYRPDHCMYGSNCKAAE 351

  Fly   281 QTGVKVIHGNRGYFHSDRQPLFKSIYGAMENYQLGSNANTEFLMPLHAALSIPSIKNSSCGKISN 345
            :.||.::|||||.:|.|:||.|:.:|.|:..|....|.......||.... :.:: |:.||:|..
Zfish   352 EEGVSILHGNRGVYHDDKQPAFRVVYDAIHEYPFEENLFQSLFYPLQTKF-LDTV-NTLCGRIPQ 414

  Fly   346 EVLK 349
            ..||
Zfish   415 VFLK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shams	NP_001097911.1	Glyco_tranf_GTA_type	48..343	CDD:299700	149/306 (49%)
shams	NP_001097911.1	RfaJ	64..>270	CDD:224359	113/216 (52%)
gxylt2	NP_001103670.1	GT8_like_2	109..412	CDD:133052	149/306 (49%)
gxylt2	NP_001103670.1	RfaJ	109..>340	CDD:224359	121/232 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	269	1.000	Domainoid score	I1805
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16823
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2499
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415297at33208
OrthoFinder	1	1.000	-	-		FOG0003370
OrthoInspector	1	1.000	-	-		otm24288
orthoMCL	1	0.900	-	-		OOG6_105081
Panther	1	1.100	-	-	O	PTHR46012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5350
SonicParanoid	1	1.000	-	-		X2261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.860