DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shams and gxylt1b

DIOPT Version :9

Sequence 1:	NP_001097911.1	Gene:	shams / 43008	FlyBaseID:	FBgn0039273	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001025270.1	Gene:	gxylt1b / 556315	ZFINID:	ZDB-GENE-041210-116	Length:	405	Species:	Danio rerio

Alignment Length:	335	Identity:	143/335 - (42%)
Similarity:	207/335 - (61%)	Gaps:	16/335 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QRPSWVTENKGKMLGYNELQTGKPPLYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFTED 87
            |||:..|.::..:...|.....:..:::..|:||:|..|.:.|:|:|:..:  :..|:|.||.|.
Zfish    54 QRPTATTSHRDVVQNPNSPVQEEVLMHLAAVACGERHGEVVNMLKTAVTLS--QRALRFHIFAEQ 116

  Fly    88 GKGDEFREKLTDWRDIKPFTFDFEILPLKFPSGNEVEWRNLFKPCAAQRLFLPSLLTHVDSLLYV 152
            ......:..|..|.......|.:.:.|:.||..:..||..||||||:||||||.:|..:||||||
Zfish   117 QLQTSIKADLDSWPAFIQGKFSYVLHPISFPHEHHEEWSQLFKPCASQRLFLPMILRELDSLLYV 181

  Fly   153 DTDILFLSPISDIWRFFKKFNETQMSALTPEHENENIGWYNRFARHPFYGRLGVNSGVMLMNLTR 217
            |||:|||.|:..||.....||.||:.|:.||||...|.||:||:.||:||::|:|||||||||||
Zfish   182 DTDVLFLQPVELIWDMLMLFNSTQLIAMAPEHEEPRIAWYSRFSWHPYYGKMGINSGVMLMNLTR 246

  Fly   218 MR-----------EMKWEQHIVSIHKEYKLRIIWGDQDIINILFYYHPDKLYIMPCEYNYRPDHC 271
            ||           .:.|::.::.:.::|||.|.|||||:|||:|:|:|:.:|.:||.:|||||||
Zfish   247 MRITQFKNDMTPVGLHWDELLMPLLQKYKLNITWGDQDLINIIFHYNPEMVYTLPCHWNYRPDHC 311

  Fly   272 MYMSICNMSQ-TGVKVIHGNRGYFHSDRQPLFKSIYGAMENYQLGSNANTEFLMPLHAALSIPSI 335
            :|.|.|..:: .||.|:|||||.||||:||.|:::|.|.|.|..|.:.....|..|..||:  ..
Zfish   312 IYGSNCAPAEDEGVFVLHGNRGVFHSDKQPAFRAVYEAFEQYTFGEDLRQSLLSRLEVALN--ET 374

  Fly   336 KNSSCGKISN 345
            .::.|||.|:
Zfish   375 THTYCGKASH 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shams	NP_001097911.1	Glyco_tranf_GTA_type	48..343	CDD:299700	136/306 (44%)
shams	NP_001097911.1	RfaJ	64..>270	CDD:224359	99/216 (46%)
gxylt1b	NP_001025270.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	46..65		4/10 (40%)
		GT8_like_2	79..382	CDD:133052	136/306 (44%)
		RfaJ	<149..>310	CDD:224359	85/160 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579624
Domainoid	1	1.000	50	1.000	Domainoid score	I11678
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2499
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415297at33208
OrthoFinder	1	1.000	-	-		FOG0003370
OrthoInspector	1	1.000	-	-		otm24288
orthoMCL	1	0.900	-	-		OOG6_105081
Panther	1	1.100	-	-	O	PTHR46012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2261
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.760