DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shams and large2

DIOPT Version :9

Sequence 1:	NP_001097911.1	Gene:	shams / 43008	FlyBaseID:	FBgn0039273	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001004538.1	Gene:	large2 / 446214	ZFINID:	ZDB-GENE-050419-253	Length:	750	Species:	Danio rerio

Alignment Length:	268	Identity:	76/268 - (28%)
Similarity:	116/268 - (43%)	Gaps:	48/268 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFTEDGKGDEFREKLTDWR--DIKPFTFDF 110
            |::..|..|......:|.:..:||| :....|.|...|:.............|.  .::...:|.
Zfish   132 LHVACVCAGHNASRDVVTLVKSILF-HRRNPLHFHFITDTVANQILSTLFQSWMVPSVQVSFYDA 195

  Fly   111 EILPLKFPSGNEVEW---------RNLFKPCAAQRLFLPSLLTHVDSLLYVDTDILFLSPISDIW 166
            :.|.      :||.|         ..|.|....:.  |||.|:.|   :.:||||.|.:.|:::|
Zfish   196 DELK------SEVSWIPNKHYSGIYGLMKLTLTKA--LPSNLSKV---IVLDTDITFATDIAELW 249

  Fly   167 RFFKKFNETQMSALTPEHENENIGWY--NRFARH---PFYGRLGVNSGVMLMNLTRMREMKWEQ- 225
            ..|:||.|.|:..|.   ||:: .||  |.:..|   |..|| |.|:||:|:.|.|:|.|.|||
Zfish   250 AIFRKFTEKQVIGLV---ENQS-DWYLGNLWKNHKPWPALGR-GFNTGVILLYLERLRRMGWEQM 309

  Fly   226 -------HIVSIHKEYKLRIIWGDQDIINILFYYHPDKLYIMPCEYNYR-PDHCMYMSICNMSQT 282
                   .::|:     |.....||||.|.....:|..::.:||.:|.: .||.. ...|....:
Zfish   310 WRLTAERELMSM-----LSTSLADQDIFNAFIKQNPVLVHQLPCFWNVQLSDHTR-SEQCYTEVS 368

  Fly   283 GVKVIHGN 290
            .:||||.|
Zfish   369 DLKVIHWN 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shams	NP_001097911.1	Glyco_tranf_GTA_type	48..343	CDD:299700	76/268 (28%)
shams	NP_001097911.1	RfaJ	64..>270	CDD:224359	65/230 (28%)
large2	NP_001004538.1	GT8_LARGE_C	132..411	CDD:133053	76/268 (28%)
		Xylosyltransferase activity. /evidence=ECO:0000250\|UniProtKB:O95461	132..407		76/268 (28%)
		Glucuronyltransferase activity. /evidence=ECO:0000250\|UniProtKB:O95461	408..750
		Glyco_transf_49	467..736	CDD:316419
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579619
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740