DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shams and large1

DIOPT Version :9

Sequence 1:	NP_001097911.1	Gene:	shams / 43008	FlyBaseID:	FBgn0039273	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001004537.1	Gene:	large1 / 446213	ZFINID:	ZDB-GENE-061204-1	Length:	757	Species:	Danio rerio

Alignment Length:	272	Identity:	72/272 - (26%)
Similarity:	118/272 - (43%)	Gaps:	56/272 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFTEDGKGDEFREKL--------------T 98
            ::|.:|..|......:|.:..::|| :....|.|.|.|     |....|:              .
Zfish   139 IHIAIVCAGYNASRDVVTLVKSVLF-HRRNPLHFHIIT-----DSIARKILADLFHTWMVPAVHV 197

  Fly    99 DWRDIKPFTFDFEILPLKFPSGNEVEWRNLFKPCAAQRLFLPSLL-THVDSLLYVDTDILFLSPI 162
            ::.|......:...:|.|..||..          ...:|.|...| :.::.::.:||||.|.:.|
Zfish   198 NFYDADELKSEVSWIPNKHYSGIH----------GLMKLVLTKTLPSDLEKVIVLDTDITFATDI 252

  Fly   163 SDIWRFFKKFNETQMSALTPEHENENIGWY--NRFARH---PFYGRLGVNSGVMLMNLTRMREMK 222
            :::|..|.||...|:..|.   ||:: .||  |.:..|   |..|| |.|:||:|:.|.|:|::|
Zfish   253 AELWVVFHKFKGQQVLGLV---ENQS-DWYLGNLWKNHRPWPALGR-GFNTGVILLLLDRLRKLK 312

  Fly   223 WEQ--------HIVSIHKEYKLRIIWGDQDIINILFYYHPDKLYIMPCEYNYR-PDHCMYMSICN 278
            |||        .::|:     |.....||||.|.:...:|..::.:||.:|.: .||.. ...|.
Zfish   313 WEQMWRLTAERELMSM-----LSTSLADQDIFNAVIKQNPFLVHQLPCYWNVQLSDHTR-SEKCY 371

  Fly   279 MSQTGVKVIHGN 290
            ...:.:||||.|
Zfish   372 KDVSDLKVIHWN 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shams	NP_001097911.1	Glyco_tranf_GTA_type	48..343	CDD:299700	72/272 (26%)
shams	NP_001097911.1	RfaJ	64..>270	CDD:224359	61/234 (26%)
large1	NP_001004537.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	76..127
		RfaJ	137..>387	CDD:224359	72/272 (26%)
		GT8_LARGE_C	139..418	CDD:133053	72/272 (26%)
		Xylosyltransferase activity. /evidence=ECO:0000250\|UniProtKB:O95461	139..414		72/272 (26%)
		Glucuronyltransferase activity. /evidence=ECO:0000250\|UniProtKB:O95461	415..757
		Glyco_transf_49	474..743	CDD:290607
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840