DRSC/TRiP Functional Genomics Resources

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Protein Alignment shams and Large1

DIOPT Version :9

Sequence 1:NP_001097911.1 Gene:shams / 43008 FlyBaseID:FBgn0039273 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_001304320.1 Gene:Large1 / 16795 MGIID:1342270 Length:756 Species:Mus musculus


Alignment Length:284 Identity:77/284 - (27%)
Similarity:131/284 - (46%) Gaps:34/284 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 TEN-KGKMLGYNELQTGKPP-------LYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFT 85
            :|| :..::..|..:.|:.|       :::.:|..|......:|.:..::|| :....|.|.:..
Mouse   111 SENLRAGIVAGNSSECGQQPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLF-HRRNPLHFHLIA 174

  Fly    86 EDGKGDEFREKLTDWRDIKPFTFDF-EILPLKFPSGNEVEW---RNLFKPCAAQRLFLPSLL-TH 145
             |...::....|.....:.....|| ....||    :||.|   ::........:|.|...| .:
Mouse   175 -DSIAEQILATLFQTWMVPAVRVDFYNADELK----SEVSWIPNKHYSGIYGLMKLVLTKTLPAN 234

  Fly   146 VDSLLYVDTDILFLSPISDIWRFFKKFNETQMSALTPEHENENIGWY--NRFARH---PFYGRLG 205
            ::.::.:||||.|.:.|:::|..|.||...|:..|.   ||:: .||  |.:..|   |..|| |
Mouse   235 LERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLV---ENQS-DWYLGNLWKNHRPWPALGR-G 294

  Fly   206 VNSGVMLMNLTRMREMKWEQ-HIVSIHKEY--KLRIIWGDQDIINILFYYHPDKLYIMPCEYNYR 267
            .|:||:|:.|.::|:||||| ..::..:|.  .|.....||||.|.:...:|..:|.:||.:|.:
Mouse   295 YNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQ 359

  Fly   268 -PDHCMYMSICNMSQTGVKVIHGN 290
             .||.. ...|....:.:||||.|
Mouse   360 LSDHTR-SEQCYRDVSDLKVIHWN 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shamsNP_001097911.1 Glyco_tranf_GTA_type 48..343 CDD:299700 72/257 (28%)
RfaJ 64..>270 CDD:224359 62/219 (28%)
Large1NP_001304320.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 43..64
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 82..108
GT8_LARGE_C 138..417 CDD:133053 72/257 (28%)
Xylosyltransferase activity. /evidence=ECO:0000250|UniProtKB:O95461 138..413 72/257 (28%)
Glucuronyltransferase activity. /evidence=ECO:0000250|UniProtKB:O95461 414..756
Glyco_transf_49 473..742 CDD:372794
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167836171
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.840

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