DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shams and gxylt1a

DIOPT Version :9

Sequence 1:	NP_001097911.1	Gene:	shams / 43008	FlyBaseID:	FBgn0039273	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	XP_017209692.1	Gene:	gxylt1a / 100333154	ZFINID:	ZDB-GENE-110314-1	Length:	342	Species:	Danio rerio

Alignment Length:	327	Identity:	154/327 - (47%)
Similarity:	211/327 - (64%)	Gaps:	24/327 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PLYIVVVSCGQRVQETLVMIKSAILFNYDEEYLKFVIFTEDGKGDEFREKLTDWRDIKPFTFDFE 111
            |:.:.||:||.|:||||.|||||::|:..|  |.|.||.|:.....||:.|..|.......|.:.
Zfish    14 PVQLAVVACGSRLQETLTMIKSAVIFSRSE--LHFHIFAEEDLHAGFRDTLQSWPQRVRSRFSYS 76

  Fly   112 ILPLKFPSGNEVEWRNLFKPCAAQRLFLPSLLTHVDSLLYVDTDILFLSPISDIWRFFKKFNETQ 176
            |.|:.|||.|..|||.||||||:||||||.:|..|||:||||||||||.|:.|||.|...||.:.
Zfish    77 IYPISFPSENAREWRKLFKPCASQRLFLPLILKQVDSVLYVDTDILFLRPVEDIWSFLSSFNRSH 141

  Fly   177 MSALTPEHENENIGWYNRFARHPFYGRLGVNSGVMLMNLTRMR-----------EMKWEQHIVSI 230
            ::||.||||...:||||||||||:||:.||||||||:|:||:|           ::.|...::.:
Zfish   142 VAALAPEHEEPRMGWYNRFARHPYYGKTGVNSGVMLINMTRIRHTHFKNDLSAMDLSWSDLLMPL 206

  Fly   231 HKEYKLRIIWGDQDIINILFYYHPDKLYIMPCEYNYRPDHCMYMSICNMS-QTGVKVIHGNRGYF 294
            ..:|||.|.|||||::||:|:|:|:.|.:.||.:|||||||:|.|.|..: |.|:.::|||||.:
Zfish   207 LNKYKLNITWGDQDLLNIIFHYNPESLLVFPCHWNYRPDHCIYGSNCAAAEQHGIYILHGNRGVY 271

  Fly   295 HSDRQPLFKSIYGAMENYQLGSNANTEFLMPLHAALSIPSIKNSSCGKISNEVLKVANAVVTKRY 359
            |.|:||.|.::|.|::.|....:.....|.||...|.  |.:::.||::.:        :.|||.
Zfish   272 HDDKQPAFSAVYNAIQQYAFEDDLLHGLLDPLEEKLK--SSEHTYCGRVRH--------IFTKRL 326

  Fly   360 RE 361
            ||
Zfish   327 RE 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shams	NP_001097911.1	Glyco_tranf_GTA_type	48..343	CDD:299700	148/306 (48%)
shams	NP_001097911.1	RfaJ	64..>270	CDD:224359	111/216 (51%)
gxylt1a	XP_017209692.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579623
Domainoid	1	1.000	269	1.000	Domainoid score	I1805
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2499
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415297at33208
OrthoFinder	1	1.000	-	-		FOG0003370
OrthoInspector	1	1.000	-	-		otm24288
orthoMCL	1	0.900	-	-		OOG6_105081
Panther	1	1.100	-	-	LDO	PTHR46012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5350
SonicParanoid	1	1.000	-	-		X2261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790