Protein Alignment CG11836 and KLK4

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 75/237 - (31%)
• Similarity: 123/237 - (51%)
• Gaps: 19/237 - (8%)

  Fly    96 RIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITS 160
            :|:.|:....:..||.|.:|.:.:..|.|.|:...:|||||||.    ::...:..|.|..|...
Human    30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLGLHSLEADQ 90

  Fly   161 E--SQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGTVVG 223
            |  ||.::.:::  ::|..::.....||:.|::|.:.:|.|..|:.|.:.. ....||....|.|
Human    91 EPGSQMVEASLS--VRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS-QCPTAGNSCLVSG 152

  Fly   224 WGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCA--GRPSMDSCQGDSGGPLLLS 286
            ||..: .|.:|:::..|.|.::|...|  .:........||.||  |:...|||.|||||| |:.
Human   153 WGLLA-NGRMPTVLQCVNVSVVSEEVC--SKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGP-LIC 213

  Fly   287 NGVKYFIVGIVSWG-VGCGREGYPGVYSRVSKFIPWIKSNLE 327
            ||   ::.|:||:| ..||:.|.||||:.:.||..||:..::
Human   214 NG---YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	75/232 (32%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	75/232 (32%)