Protein Alignment CG11836 and TMPRSS11D

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 106/371 - (28%)
• Similarity: 162/371 - (43%)
• Gaps: 67/371 - (18%)

  Fly     9 FWMLTANYSSVL----SLEY-----------SKGFNESDAINTIHTGH----------------- 41
            |.:|...|:|.|    :.||           :|.|.||:..|.....|
Human    54 FQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVM 118

  Fly    42 --------NKRTSKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCG-----FSNE 93
                    |..:.|...:::.|.....|....::.:.:....|:.::......:||     .:..
Human   119 KFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLS 183

  Fly    94 EIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKK-------LRKSKIRVIF 151
            |.||:||.......:||...:..:...||||||:...::|:||||.:.       :..|.|...|
Human   184 EQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTF 248

  Fly   152 GDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYD-PA 215
                       ..::..|..::.|.::...|:.|||||:||...::|:|.|..:|||....: |.
Human   249 -----------PKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPP 302

  Fly   216 GRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAGRP--SMDSCQGD 278
            |....|.|||.....|.....:.|.:|.|:|...|......:..|.|.|||||.|  .:|:||||
Human   303 GSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGD 367

  Fly   279 SGGPLLLSNGVK-YFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIK 323
            |||||:..:..: :|||||||||..||....||||:||:.::.||:
Human   368 SGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIR 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	84/238 (35%)
TMPRSS11D	NP_004253.1	SEA	48..146	CDD:460188	16/91 (18%)
		Tryp_SPc	187..415	CDD:238113	84/238 (35%)