DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11836 and tmprss7

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_002666699.2	Gene:	tmprss7 / 798480	ZFINID:	ZDB-GENE-130530-883	Length:	840	Species:	Danio rerio

Alignment Length:	397	Identity:	116/397 - (29%)
Similarity:	180/397 - (45%)	Gaps:	106/397 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NESDAINTIHTGHNKRTSKFLFDTIFRISSGV-----SNAFGLSDTEDEVE-------------- 74
            |.....:..::.:|  ||:...||.|..|:|:     ....||.|.:||.:
Zfish   454 NADQPFSATYSSYN--TSQPCPDTHFLCSTGLCVEKSKRCDGLDDCQDESDEIFCSKPPKFCGGT 516

  Fly    75 ------YTENSSL--------------------------------KNCDC----DCGFSNEEIRI 97
                  |..|..:                                ||..|    ||...::|...
Zfish   517 SPLHPLYICNGEMDCSSGKDETNCTQETSCSGVSYQCDNGACILKKNAKCDGFPDCFDQSDEKNC 581

  Fly    98 VGGKPT-----------------GVN----QYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKK 141
            ..||||                 |||    ::||...:.:.|:.:||.|:|:..:::|||||..|
Zfish   582 ACGKPTHVKRVLDGTSPQQRIVGGVNAVEGEWPWQVSMHFSGQLYCGASVLSDVWLISAAHCYSK 646

  Fly   142 LRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRK--PISFSKIIKP 204
            .|.:..|:... |...:...|......:..::.|:.::...::.|||||:|:|  |....:.|:|
Zfish   647 ERLADPRMWMA-HLGMLNQGSAKHVAEIRRIVVHEYYNARNFDYDIALLQLKKVWPSGLEQYIQP 710

  Fly   205 ICLPRYNYDPA-----GRIGTVVGWGRTSEGGE-LPSIVNQVKVPIMSITECRNQRYKSTRITSS 263
            :|||.    |:     |....|.|||..||..: ||:::.:.:|.::|.:||: :.|..  ::..
Zfish   711 VCLPA----PSQTFTEGHRCWVTGWGYRSEQDKVLPTVLQKAEVNVLSQSECK-RSYGP--VSPR 768

  Fly   264 MLCAGRPS--MDSCQGDSGGPL--LLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKS 324
            |||||.||  .|:|:|||||||  ....|.::|:.||||||.||||...||||:||:|||.||:.
Zfish   769 MLCAGVPSGEQDACRGDSGGPLSCQAQTGSRWFLTGIVSWGSGCGRPYLPGVYTRVAKFIDWIQR 833

  Fly   325 NL--ENT 329
            ::  ||:
Zfish   834 HIHDENS 840

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	92/260 (35%)
tmprss7	XP_002666699.2	SEA	99..203	CDD:307516
		CUB	<260..344	CDD:238001
		CUB	367..465	CDD:294042	1/10 (10%)
		LDLa	472..506	CDD:238060	10/33 (30%)
		LDLa	546..581	CDD:238060	6/34 (18%)
		Tryp_SPc	601..831	CDD:214473	86/237 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920