DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Prss44

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_683742.2	Gene:	Prss44 / 73336	MGIID:	1920586	Length:	372	Species:	Mus musculus

Alignment Length:	249	Identity:	90/249 - (36%)
Similarity:	133/249 - (53%)	Gaps:	19/249 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 CGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFG 152
            ||  :...|||||:|....::||...:....:..|||||::|.:|::|||||  .......|..|
Mouse   105 CG--HRTARIVGGRPAPARKWPWQVSLQVHKQHICGGSLISKWWVITAAHCV--YGHLDYAVFMG 165

  Fly   153 DHDQEITSESQAIQRAVTAVIKHKSFD-PDTYNNDIALLRLRKPISFSKIIKPICLPRYNY--DP 214
            |.|   ....:.::..|..:|.|:.|. ..|..:||||:.|..|:::|..|:|:|:|..::  .|
Mouse   166 DAD---LWSKRPVRIPVQDIIVHQDFSMMRTVVHDIALVLLAFPVNYSVNIQPVCIPEKSFLVQP 227

  Fly   215 AGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKS------TRITSSMLCA-GRPSM 272
             |.:..|.|||:..|.|....|:.::::.|:...:| ||..|.      |.:....:|. .....
Mouse   228 -GTLCWVTGWGKVLEQGRSSRILQEIELNIIRHEKC-NQILKDIMGNIFTLVQEGGVCGYNEKGG 290

  Fly   273 DSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNL 326
            |:|||||||||:......:..|||||||:||||.||||||:.||.:..||...|
Mouse   291 DACQGDSGGPLVCEFNKTWVQVGIVSWGLGCGRIGYPGVYTEVSYYRDWIIKEL 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/237 (36%)
Prss44	NP_683742.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..72
		Tryp_SPc	111..340	CDD:214473	85/235 (36%)
		Tryp_SPc	112..340	CDD:238113	84/234 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920