Protein Alignment CG11836 and TMPRSS2

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_001128571.1
• Gene: TMPRSS2 / 7113
• HGNCID: 11876
• Length: 529
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 100/314 - (31%)
• Similarity: 153/314 - (48%)
• Gaps: 68/314 - (21%)

  Fly    59 GVSNAF----GLSDTEDEVEYTE-NSSLKNCD----------CD-----------CGF---SNEE 94
            |..|.|    |:.|......:.: |:|..|.|          |.           ||.   |:.:
Human   226 GYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQ 290

  Fly    95 IRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKK--------------LRKS 145
            .|||||:......:||...:.......||||::|.:::::|||||:|              ||:|
Human   291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQS 355

  Fly   146 KIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRY 210
              .:.:|...|            |..||.|.::|..|.||||||::|:||::|:.::||:|||
Human   356 --FMFYGAGYQ------------VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP-- 404

  Fly   211 NYDPA-----GRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG-- 268
              :|.     .::..:.|||.|.|.|:...::|..||.::....|.::......||.:|:|||
Human   405 --NPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFL 467

  Fly   269 RPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWI 322
            :.::|||||||||||:.|....::::|..|||.||.:...||||..|..|..||
Human   468 QGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/247 (35%)
TMPRSS2	NP_001128571.1	LDLa	150..185	CDD:238060
		SRCR_2	190..283	CDD:464747	11/56 (20%)
		Tryp_SPc	293..524	CDD:238113	86/247 (35%)